Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.44 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.42 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.42 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31155098 | 0.84 | ALDH1A1 (0.42) | ENPP2ORAI1ORAI2ORAI3LIPG | |
| SCHEMBL910660 | 0.80 | ALDH1A1 (0.44) | ENPP2ORAI1ORAI2ORAI3MGLL | |
| SCHEMBL27815400 | 0.77 | ALDH1A1 (0.46) | CA4CA6CA7CA14CA1 | |
| SCHEMBL1396708 | 0.77 | MGLL (0.38) | ENPP2ORAI1ORAI2ORAI3MGLL | |
| SCHEMBL346128 | 0.76 | ENPP2 (0.57) | ENPP2ORAI1ORAI2ORAI3MGLL | |
| SCHEMBL2399704 | 0.75 | MAPT (0.44) | ENPP2ORAI1ORAI2ORAI3LIPG | |
| SCHEMBL29595177 | 0.75 | MAPT (0.44) | ENPP2ORAI1ORAI2ORAI3LIPG | |
| SCHEMBL61913 | 0.75 | ALDH1A1 (0.50) | ENPP2LIPGCA4CA6CA5A | |
| SCHEMBL18171925 | 0.73 | LIPE (0.44) | ENPP2ORAI1ORAI2ORAI3LIPE | |
| SCHEMBL18171928 | 0.73 | LIPE (0.44) | ENPP2ORAI1ORAI2ORAI3LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6566429-B2 | Mixture of polymer and aromatic boronic compound | UNIVERSITY OF SOUTH CAROLINA | 2003-05-20 | — | — | US | disclosed |