Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442974 | 0.81 | NPC1 (0.51) | L3MBTL1SMN1; SMN2LMNAALDH1A1HSD17B10 | |
| SCHEMBL9190522 | 0.80 | MAOB (0.51) | L3MBTL1LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL8442795 | 0.80 | CHRNB2 (0.45) | TSHRL3MBTL1SMN1; SMN2RXFP1PTGER4 | |
| SCHEMBL14693750 | 0.79 | PTGS2 (0.51) | TSHRSMN1; SMN2PTGER4PTGER3PTGER2 | |
| SCHEMBL23964581 | 0.77 | PTGER4 (0.60) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL13344106 | 0.76 | GABRA1 (0.43) | TSHRL3MBTL1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8442964 | 0.76 | SMN1; SMN2 (0.43) | TSHRL3MBTL1SMN1; SMN2RXFP1PTGER4 | |
| SCHEMBL29245150 | 0.76 | SCN8A (0.36) | TSHRL3MBTL1SMN1; SMN2PTGER4PTGER3 | |
| SCHEMBL21438076 | 0.75 | NLRP3 (0.47) | SMN1; SMN2LMNAALDH1A1HSD17B10KDM4E | |
| SCHEMBL28860149 | 0.75 | SCN8A (0.38) | TSHRPTGER4PTGER3PTGER2PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2550313-B1 | METHOD OF MAKING POLYCARBONATE | SABIC INNOVATIVE PLASTICS IP (NL) | 2014-04-23 | — | — | EP | claimed |
| EP-2550313-A1 | METHOD OF MAKING POLYCARBONATE | SABIC Innovative Plastics IP B.V. (NL) | 2013-01-30 | — | — | EP | claimed |
| WO-2011117774-A1 | METHOD OF MAKING POLYCARBONATE | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2011-09-29 | — | — | WO | claimed |
| US-7985824-B1 | Method of making polycarbonate | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2011-07-26 | — | — | US | claimed |
| EP-1940913-B1 | METHODS FOR PREPARING TRANSPARENT ARTICLES FROM BIPHENOL POLYCARBONATE COPOLYMERS | SABIC INNOVATIVE PLASTICS IP (NL) | 2011-06-15 | — | — | EP | claimed |
| EP-1740637-B1 | ALIPHATIC DIOL POLYCARBONATES AND THEIR PREPARATION | SABIC INNOVATIVE PLASTICS IP (NL) | 2010-02-17 | — | — | EP | claimed |
| EP-1940913-A2 | METHODS FOR PREPARING TRANSPARENT ARTICLES FROM BIPHENOL POLYCARBONATE COPOLYMERS | General Electric Company (US) | 2008-07-09 | — | — | EP | claimed |
| US-7348394-B2 | Methods for preparing transparent articles from biphenol polycarbonate copolymers | GENERAL ELECTRIC COMPANY (US) | 2008-03-25 | — | — | US | claimed |
| JP-2008508361-A | — | — | 2008-03-21 | — | — | JP | claimed |
| US-7312352-B2 | Method of preparing ester-substituted diaryl carbonates | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2007-12-25 | — | — | US | claimed |
| US-20070055025-A1 | Methods for producing and purifying 2-hydrocarbyl-3,3-bis(4-hydroxyaryl)phthalimidine monomers and polycarbonates derived therefrom | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2007-03-08 | — | — | US | claimed |
| EP-1740637-A1 | ALIPHATIC DIOL POLYCARBONATES AND THEIR PREPARATION | General Electric Company A Corporation of the State of New York (US) | 2007-01-10 | — | — | EP | claimed |
| US-7138479-B2 | Aliphatic diol polycarbonates and their preparation | GENERAL ELECTRIC COMPANY (US) | 2006-11-21 | — | — | US | claimed |
| WO-2006017550-A1 | METHOD OF PREPARING ESTER-SUBSTITUTED DIARYL CARBONATES | GENERAL ELECTRIC COMPANY (US) | 2006-02-16 | — | — | WO | claimed |
| US-20060025622-A1 | Method of preparing ester-substituted diaryl carbonates | GENERAL ELECTRIC COMPANY (US) | 2006-02-02 | — | — | US | claimed |
| WO-2006012162-A2 | METHODS FOR PRODUCING AND PURIFYING 2-HYDROCARBYL-3,3-BIS(4-HYDROXYARYL)PHTHALIMIDINE MONOMERS AND POLYCARBONATES DERIVED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2006-02-02 | — | — | WO | claimed |
| US-20050288517-A1 | Methods for producing and purifying 2-hydrocarbyl-3,3-bis(4-hydroxyaryl)phthalimidine monomers and polycarbonates derived therefrom | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2005-12-29 | — | — | US | claimed |
| US-20050222334-A1 | Methods for producing and purifying 2-hydrocarbyl-3,3-bis(4-hydroxyaryl)phthalimidine monomers and polycarbonates derived therefrom | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2005-10-06 | — | — | US | claimed |
| WO-2005066239-A1 | ALIPHATIC DIOL POLYCARBONATES AND THEIR PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2005-07-21 | — | — | WO | claimed |
| US-20050143554-A1 | ALIPHATIC DIOL POLYCARBONATES AND THEIR PREPARATION | GENERAL ELECTRIC COMPANY | 2005-06-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025622-A1 | Method of preparing ester-substituted diaryl carbonates | PHOSPHO1, MED23, PLA2G2C | TSHR 4474/4885L3MBTL1 4390/4885SMN1; SMN2 3223/4885 |
| US-20070055025-A1 | Methods for producing and purifying 2-hydrocarbyl-3,3-bis(4-hydroxyaryl)phthalimidine monomers and polycarbonates derived therefrom | PBRM1, PHF2, PAH | TSHR 3618/4885L3MBTL1 2186/4885SMN1; SMN2 4786/4885 |
| US-20050288517-A1 | Methods for producing and purifying 2-hydrocarbyl-3,3-bis(4-hydroxyaryl)phthalimidine monomers and polycarbonates derived therefrom | PBRM1, PHF2, PAH | TSHR 3618/4885L3MBTL1 2186/4885SMN1; SMN2 4786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.