Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442795 | 0.83 | CHRNB2 (0.45) | SMN1; SMN2L3MBTL1ALDH1A1NPC1LMNA | |
| SCHEMBL9711647 | 0.77 | SMN1; SMN2 (0.58) | SMN1; SMN2TRPM8TP53CHRM2CHRM1 | |
| SCHEMBL3084308 | 0.76 | ALDH1A1 (0.50) | SMN1; SMN2TRPM8TP53CHRM2CHRM1 | |
| SCHEMBL716643 | 0.76 | TSHR (0.43) | SMN1; SMN2L3MBTL1ALDH1A1NPC1LMNA | |
| SCHEMBL8858645 | 0.74 | TRPM8 (0.41) | SMN1; SMN2TRPM8TP53CHRM2CHRM1 | |
| SCHEMBL8858643 | 0.74 | TRPM8 (0.41) | SMN1; SMN2TRPM8TP53CHRM2CHRM1 | |
| SCHEMBL11432478 | 0.73 | TP53 (0.51) | SMN1; SMN2TRPM8TP53CHRM2CHRM1 | |
| SCHEMBL28230483 | 0.73 | TP53 (0.54) | SMN1; SMN2TRPM8TP53CHRM2CHRM1 | |
| SCHEMBL5615999 | 0.72 | NPC1 (0.50) | SMN1; SMN2TRPM8TP53CHRM2CHRM1 | |
| SCHEMBL7662318 | 0.72 | TRPM8 (0.39) | SMN1; SMN2TRPM8TP53CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939563-A | FUNGICIDES | ZENECA LIMITED (GB) | 1999-08-17 | — | — | US | disclosed |
| US-5777162-A | Intermediates for the preparation of fungicides | ZENECA LIMITED (GB) | 1998-07-07 | — | — | US | disclosed |