Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 2/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL117789 | 0.90 | TAS1R3 (0.40) | TAS1R3TAS1R1MEP1BALDH1A1KDM4E | |
| SCHEMBL29769728 | 0.89 | KDM4E (0.38) | TAS1R3TAS1R1MEP1BALDH1A1KDM4E | |
| SCHEMBL679753 | 0.89 | KDM4E (0.38) | TAS1R3TAS1R1MEP1BALDH1A1KDM4E | |
| SCHEMBL1114950 | 0.88 | TAS1R3 (0.38) | TAS1R3TAS1R1MEP1BALDH1A1KDM4E | |
| SCHEMBL721119 | 0.85 | MEP1B (0.37) | TAS1R3TAS1R1MEP1BALDH1A1KDM4E | |
| SCHEMBL11913395 | 0.85 | TAS1R3 (0.36) | TAS1R3TAS1R1MEP1BALDH1A1KDM4E | |
| SCHEMBL1115268 | 0.84 | TAS1R3 (0.39) | TAS1R3TAS1R1MEP1BALDH1A1KDM4E | |
| SCHEMBL1654712 | 0.84 | MEP1B (0.38) | TAS1R3TAS1R1MEP1BALDH1A1KDM4E | |
| SCHEMBL22366793 | 0.84 | ACLY (0.37) | TAS1R3TAS1R1MEP1BALDH1A1KDM4E | |
| SCHEMBL1654715 | 0.84 | MEP1B (0.38) | TAS1R3TAS1R1MEP1BALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053053-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-03-01 | — | — | US | disclosed |
| US-20120053053-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-03-01 | — | — | US | disclosed |
| US-20120053053-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-03-01 | — | — | US | disclosed |
| EP-2396306-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | Syngenta Limited (GB) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010092339-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010092339-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2010-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053053-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | DPYD, DHODH, TYMP | TAS1R3 3047/4885TAS1R1 2947/4885MEP1B 3098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.