Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495300 | 0.88 | LMNA (0.46) | ALDH1A1RECQLMAPTKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7163638 | 0.87 | LMNA (0.45) | ALDH1A1RECQLMAPTKMT2AMEN1 | |
| SCHEMBL7168001 | 0.83 | ALDH1A1 (0.54) | ALDH1A1USP2SMN1; SMN2RECQLMAPT | |
| SCHEMBL7167703 | 0.82 | TSHR (0.44) | ALDH1A1MAPTKDM4EKMT2AL3MBTL1 | |
| SCHEMBL7167706 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EKMT2AL3MBTL1 | |
| SCHEMBL6968719 | 0.79 | LMNA (0.52) | ALDH1A1SMN1; SMN2MAPTKDM4EKMT2A | |
| SCHEMBL7171303 | 0.79 | ALDH1A1 (0.47) | ALDH1A1USP2SMN1; SMN2RECQLMAPT | |
| SCHEMBL6961863 | 0.77 | CHRM2 (0.57) | ALDH1A1LTA4H | |
| SCHEMBL7172628 | 0.77 | CHRM2 (0.54) | ALDH1A1KDM4ELTA4H | |
| SCHEMBL6959063 | 0.76 | DRD2 (0.52) | SMN1; SMN2MAPTKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569849-B1 | N-Substituted azaheterocyclic compounds | NOVO NORDISK A/S (DK) | 2003-05-27 | — | — | US | disclosed |
| EP-0934306-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015546-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-04-16 | — | — | WO | disclosed |