Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7167706 | 0.83 | ALDH1A1 (0.48) | KDM4EKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL7170838 | 0.83 | ALDH1A1 (0.53) | TSHRKDM4EKMT2AALDH1A1HPGD | |
| SCHEMBL7170834 | 0.83 | ALDH1A1 (0.53) | TSHRKDM4EKMT2AALDH1A1HPGD | |
| SCHEMBL7167704 | 0.82 | ALDH1A1 (0.46) | KDM4EKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL6968719 | 0.78 | LMNA (0.52) | KDM4EKMT2AALDH1A1POLBMAPT | |
| SCHEMBL7172628 | 0.76 | CHRM2 (0.54) | KDM4EALDH1A1 | |
| SCHEMBL6961863 | 0.76 | CHRM2 (0.57) | ALDH1A1 | |
| SCHEMBL7163618 | 0.75 | ALDH1A1 (0.61) | TSHRKDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL7168069 | 0.75 | MTNR1A (0.46) | TSHRKDM4EKMT2AALDH1A1POLB | |
| SCHEMBL6959063 | 0.75 | DRD2 (0.52) | TSHRKDM4EKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569849-B1 | N-Substituted azaheterocyclic compounds | NOVO NORDISK A/S (DK) | 2003-05-27 | — | — | US | disclosed |
| EP-0934306-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015546-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-04-16 | — | — | WO | disclosed |