Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CCR8 | P51685 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7168049 | 0.91 | HSD17B10 (0.49) | ALDH1A1KMT2AL3MBTL1KDM4ETHRB | |
| SCHEMBL5495301 | 0.89 | SLC6A1 (0.42) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7163639 | 0.88 | SLC6A1 (0.41) | ALDH1A1 | |
| SCHEMBL7167703 | 0.83 | TSHR (0.44) | ALDH1A1KMT2AL3MBTL1KDM4EMEN1 | |
| SCHEMBL7167704 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KMT2AL3MBTL1KDM4ECCR8 | |
| SCHEMBL6968719 | 0.78 | LMNA (0.52) | ALDH1A1KMT2AL3MBTL1LMNAKDM4E | |
| SCHEMBL5495268 | 0.78 | DRD2 (0.43) | — | |
| Hydrochloric Acid SCHEMBL7167860 | 0.77 | DRD2 (0.42) | KMT2ALMNAKDM4ETHRBMEN1 | |
| SCHEMBL7172628 | 0.76 | CHRM2 (0.54) | ALDH1A1KDM4ETHRBLTA4H | |
| SCHEMBL6961863 | 0.76 | CHRM2 (0.57) | ALDH1A1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569849-B1 | N-Substituted azaheterocyclic compounds | NOVO NORDISK A/S (DK) | 2003-05-27 | — | — | US | disclosed |
| EP-0934306-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015546-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-04-16 | — | — | WO | disclosed |