Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 7/20 | 0.54 |
| ▸ | PDE6C | P51160 | 2/20 | 0.54 |
| ▸ | SLC7A11 | Q9UPY5 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5085819 | 0.92 | PDE5A (0.65) | PDE5APDE6CALDH1A1MAPTMEN1 | |
| SCHEMBL1872915 | 0.91 | PDE5A (0.58) | PDE5APDE6CALDH1A1MAPTMEN1 | |
| SCHEMBL6058528 | 0.78 | PDE5A (0.67) | PDE5APDE6CALDH1A1MAPTHSD17B10 | |
| SCHEMBL7019550 | 0.74 | PDE5A (0.46) | PDE5APDE6CKMT2AHSD17B10PDE4B | |
| SCHEMBL5085823 | 0.73 | PDE5A (0.56) | PDE5APDE6CALDH1A1MAPTMEN1 | |
| SCHEMBL5990273 | 0.72 | PDE5A (0.50) | PDE5APDE6CALDH1A1MAPTMEN1 | |
| SCHEMBL147337 | 0.70 | PDE5A (1.00) | PDE5APDE6CALDH1A1MEN1KMT2A | |
| SCHEMBL29611957 | 0.70 | PDE5A (0.90) | PDE5APDE6C | |
| SCHEMBL146830 | 0.70 | PDE5A (0.90) | PDE5APDE6C | |
| SCHEMBL2032429 | 0.69 | PDE5A (0.78) | PDE5APDE6C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003047588-A1 | KIT FOR REDUCING ACHING CAUSED BY PDE-V INHIBITORS | PFIZER LIMITED (GB) | 2003-06-12 | — | — | WO | disclosed |