Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637275 | 0.85 | ALDH1A1 (0.43) | PPARGALDH1A1PPARAMAPTKDM4E | |
| SCHEMBL9255616 | 0.79 | PPARG (0.43) | PPARGALDH1A1PPARAMAPTKDM4E | |
| SCHEMBL11684026 | 0.77 | VDR (0.39) | PPARGALDH1A1PPARACYP2C19CYP1A2 | |
| SCHEMBL1618680 | 0.75 | PPARG (0.44) | PPARGALDH1A1PPARAMAPTKDM4E | |
| SCHEMBL5071825 | 0.74 | ALOX15 (0.50) | ALDH1A1CYP2C19CYP1A2MEN1KMT2A | |
| SCHEMBL10547358 | 0.74 | PPARG (0.43) | PPARGALDH1A1PPARAMAPTKDM4E | |
| SCHEMBL11383504 | 0.73 | PPARG (0.46) | PPARGPPARAMAPTKDM4ECYP2C19 | |
| Lithium Ion SCHEMBL9303151 | 0.73 | PPARG (0.43) | PPARGALDH1A1PPARAMAPTKDM4E | |
| SCHEMBL10823116 | 0.73 | PPARG (0.43) | PPARGALDH1A1PPARAMAPTKDM4E | |
| SCHEMBL10547306 | 0.72 | ALDH1A1 (0.41) | PPARGALDH1A1PPARAMAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6555559-B1 | Prostaglandin I2 (PGI2); use as an anti-Helicobacter agent, a platelet function potentiating agent or a cervical ripening agent; side effect reduction | TORAY INDUSTRIES, INC. (JP) | 2003-04-29 | — | — | US | disclosed |
| EP-1044972-A1 | 5,6,7-TRINOR-4,8-INTER-m-PHENYLENE PGI2 DERIVATIVE AND DRUGS CONTAINING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2000-10-18 | — | — | EP | disclosed |