Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7161081 | 0.82 | ALDH1A1 (0.49) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11784915 | 0.80 | MAPT (0.43) | ALDH1A1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2229589 | 0.79 | MAPT (0.41) | ALDH1A1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL4704606 | 0.78 | TSHR (0.43) | ALDH1A1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9195179 | 0.76 | MAPT (0.45) | ALDH1A1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7509360 | 0.76 | HSD11B1 (0.43) | ALDH1A1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9195182 | 0.76 | MAPT (0.45) | ALDH1A1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2592 | 0.75 | CES2 (0.43) | ALDH1A1MAPTSMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL282530 | 0.75 | MAPT (0.50) | ALDH1A1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7525367 | 0.74 | KMT2A (0.61) | ALDH1A1MAPTRAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966454-B1 | DISUBSTITUTED BICYCLIC HETEROCYCLES, THEIR PRODUCTION AND USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-05-07 | — | — | EP | claimed |