Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6276281 | 0.78 | MAPT (0.56) | MAPTRAB9ACASP3SENP8SENP7 | |
| SCHEMBL10828102 | 0.78 | MAPT (0.56) | MAPTRAB9ACASP3SENP8SENP7 | |
| SCHEMBL283224 | 0.77 | ALDH1A1 (0.51) | MAPTRAB9ATSHRKMT2ASMN1; SMN2 | |
| SCHEMBL5700418 | 0.77 | TSHR (0.47) | MAPTRAB9ACASP3SENP8SENP7 | |
| SCHEMBL7277924 | 0.77 | HTR3E (0.50) | RAB9ACASP3SENP8SENP7SENP6 | |
| SCHEMBL7168201 | 0.75 | ALDH1A1 (0.46) | MAPTRAB9ACASP3SENP8SENP7 | |
| SCHEMBL5690919 | 0.74 | LMNA (0.55) | MAPTRAB9AL3MBTL1TSHRKMT2A | |
| SCHEMBL834716 | 0.73 | NOS3 (0.48) | MAPTRAB9ACASP3SENP8SENP7 | |
| SCHEMBL1515208 | 0.73 | MAPT (0.41) | MAPTRAB9ACASP3SENP8SENP7 | |
| SCHEMBL9595339 | 0.72 | CYP3A4 (0.53) | MAPTTSHRKMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439238-B2 | Antiparasitic artemisinin derivatives (endoperoxides) | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (HK) | 2008-10-21 | — | — | US | claimed |
| US-20070191354-A1 | Antiparasitic artemisinin derivatives (endoperoxides) | BAYER AKTIENGESELLSCHAFT (DE) | 2007-08-16 | — | — | US | claimed |
| US-20070021409-A1 | Antiparasitic artemisinin derivatives (endoperoxides) | BAYER AKTIENGESELLSCHAFT (DE) | 2007-01-25 | — | — | US | claimed |
| EP-1655302-A2 | ANTIPARASITIC ARTEMISININ DERIVATIVES (ENDOPEROXIDES) | Bayer HealthCare AG (DE) | 2006-05-10 | — | — | EP | claimed |
| EP-1095043-A1 | TRIOXANE DERIVATIVES | The Hong Kong University of Science & Technology (HK) | 2001-05-02 | — | — | EP | claimed |
| EP-1095042-A1 | ANTIPARASITIC ARTEMISININ DERIVATIVES (ENDOPEROXIDES) | Bayer Aktiengesellschaft (DE) | 2001-05-02 | — | — | EP | claimed |
| WO-2000004024-A1 | ANTIPARASITIC ARTEMISININ DERIVATIVES (ENDOPEROXIDES) | BAYER AKTIENGESELLSCHAFT (DE) | 2000-01-27 | — | — | WO | claimed |
| WO-2000004026-A1 | TRIOXANE DERIVATIVES | THE HONG KONG UNIVERSITY OF SCIENCE & TECHNOLOGY (CN) | 2000-01-27 | — | — | WO | claimed |
| CN-111315800-B | Triazine ring-containing polymer and composition comprising same | 日产化学株式会社 | 2022-05-31 | — | — | CN | disclosed |
| CN-107849425-B | Solvent-free photocurable adhesive composition | 日产化学工业株式会社 | 2021-09-21 | — | — | CN | disclosed |
| CN-107849392-B | Film-forming composition for inkjet coating | 日产化学工业株式会社 | 2021-07-13 | — | — | CN | disclosed |
| US-20210179779-A1 | TRIAZINE-RING-CONTAINING POLYMER AND COMPOSITION INCLUDING SAME | NISSAN CHEMICAL CORPORATION (JP) | 2021-06-17 | — | — | US | disclosed |
| CN-108602953-B | Triazine ring-containing polymer and film-forming composition containing the same | 日产化学工业株式会社 | 2021-02-05 | — | — | CN | disclosed |
| CN-111315800-A | Triazine ring-containing polymer and composition comprising same | 日产化学株式会社 | 2020-06-19 | — | — | CN | disclosed |
| US-RE34918-E | Antihistamines, muscle relaxants | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| US-5013736-A | 5-lipoxygenase inhibitors, smooth muscle relaxants | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-05-07 | — | — | US | disclosed |
| US-5011938-A | Antimicrobials | ELI LILLY AND COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| US-4940718-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1990-07-10 | — | — | US | disclosed |
| EP-0198438-B1 | SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-18 | — | — | EP | disclosed |
| EP-0202046-A1 | 7-Substituted bicyclic pyrazolidinones | ELI LILLY AND COMPANY (US) | 1986-11-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021409-A1 | Antiparasitic artemisinin derivatives (endoperoxides) | DHPS, CASP10, FECH | MAPT 4540/4885RAB9A 1357/4885CASP3 306/4885 |
| US-20070191354-A1 | Antiparasitic artemisinin derivatives (endoperoxides) | DHPS, CASP10, FECH | MAPT 4540/4885RAB9A 1357/4885CASP3 306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.