Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7168201 | 0.78 | ALDH1A1 (0.46) | TSHRMAPTHPGDMAPK1RAB9A | |
| SCHEMBL2592 | 0.77 | CES2 (0.43) | TSHRMAPTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL1553413 | 0.73 | CES2 (0.47) | MAPTHPGDCYP2C19MAPK1HTT | |
| SCHEMBL11784915 | 0.73 | MAPT (0.43) | TSHRMAPTHPGDMAPK1RAB9A | |
| SCHEMBL11408225 | 0.73 | MAPT (0.40) | TSHRMAPTHPGDCYP2C19ALOX12 | |
| SCHEMBL282530 | 0.72 | MAPT (0.50) | TSHRMAPTHPGDRAB9ACASP3 | |
| SCHEMBL2229589 | 0.72 | MAPT (0.41) | MAPTHPGDMAPK1HTTRAB9A | |
| SCHEMBL5839905 | 0.72 | HTR3E (0.39) | TSHRMAPTHPGDCYP2C19MAPK1 | |
| SCHEMBL7162802 | 0.71 | NR4A2 (0.48) | TSHRMAPTCYP2C19MAPK1RAB9A | |
| SCHEMBL8010216 | 0.71 | CES1 (0.54) | TSHRMAPTMAPK1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979349-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007076035-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-05 | — | — | WO | disclosed |