Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713240 | 0.79 | ALOX5AP (0.37) | L3MBTL1ALOX15ALDH1A1KMT2AKDM4E | |
| SCHEMBL18229 | 0.75 | CTSK (0.35) | NPSR1ALOX15ALDH1A1KMT2AGAA | |
| SCHEMBL3809031 | 0.74 | HASPIN (0.42) | L3MBTL1MAPK1ALDH1A1KMT2AGAA | |
| SCHEMBL14834735 | 0.73 | KMT2A (0.41) | L3MBTL1NPSR1ALOX15MAPK1ALDH1A1 | |
| SCHEMBL29239939 | 0.72 | L3MBTL1 (0.35) | L3MBTL1NPSR1ALOX15MAPK1ALDH1A1 | |
| SCHEMBL5738824 | 0.71 | GAA (0.56) | L3MBTL1NPSR1MAPK1ALDH1A1KMT2A | |
| SCHEMBL7021631 | 0.71 | GPR84 (0.47) | L3MBTL1MAPK1ALDH1A1KMT2AGAA | |
| SCHEMBL6950576 | 0.71 | ALDH1A1 (0.41) | L3MBTL1NPSR1ALOX15MAPK1ALDH1A1 | |
| SCHEMBL6087224 | 0.70 | ALOX15 (0.66) | ALOX15ALDH1A1KMT2AKDM4EBRAF | |
| SCHEMBL7509985 | 0.70 | HSD17B10 (0.65) | L3MBTL1NPSR1ALOX15MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765774-B2 | 3-arylquinazolin-4-one compounds for combating invertebrate pests | BASF SE (DE) | 2014-07-01 | — | — | US | disclosed |
| EP-2403837-B1 | 3-ARYLQUINAZOLIN-4-ONE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2013-12-11 | — | — | EP | disclosed |
| US-20120053052-A1 | 3-Arylquinazolin-4-one compounds for combating invertebrate pests | BASF SE (DE) | 2012-03-01 | — | — | US | disclosed |
| EP-2403837-A1 | 3-ARYLQUINAZOLIN-4-ONE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010100189-A1 | 3-ARYLQUINAZOLIN-4-ONE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2010-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053052-A1 | 3-Arylquinazolin-4-one compounds for combating invertebrate pests | CBR3, CNPY3, RTN3 | L3MBTL1 570/4885NPSR1 70/4885ALOX15 2869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.