Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29922263 | 1.00 | ALDH1A1 (0.57) | ALDH1A1MAPK1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL31267143 | 0.93 | HPGD (0.51) | ALDH1A1MAPK1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL13104572 | 0.93 | MAPT (0.56) | ALDH1A1MAPK1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL18209634 | 0.93 | HPGD (0.51) | ALDH1A1MAPK1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL13104517 | 0.93 | MAPT (0.56) | ALDH1A1MAPK1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL13202313 | 0.91 | SMN1; SMN2 (0.62) | ALDH1A1MAPK1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL13104568 | 0.91 | MAPT (0.58) | ALDH1A1MAPK1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL13104616 | 0.91 | SMN1; SMN2 (0.62) | ALDH1A1MAPK1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL13104533 | 0.91 | MAPT (0.58) | ALDH1A1MAPK1LMNASMN1; SMN2MAPT | |
| SCHEMBL26887084 | 0.91 | NLRP3 (0.61) | ALDH1A1MAPK1LMNAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4069240-A | GROUP 8 METAL CATALYST | UNIROYAL, INC. (US) | 1978-01-17 | — | — | US | claimed |
| US-3962302-A | Production of isocyanates from esters of carbamic acids (urethanes) | ATLANTIC RICHFIELD COMPANY (US) | 1976-06-08 | — | — | US | claimed |
| WO-2023008572-A1 | ONIUM SALT, BLOCKING AGENT DISSOCIATION CATALYST FOR BLOCKED ISOCYANATE, BLOCKED ISOCYANTE COMPOSITION INCLUDING BLOCKING AGENT DISSOCIATION CATALYST, THERMOSETTING RESIN COMPOSITION, AND CURED PRODUCT AND MANUFACTURING METHOD THEREFOR | 広栄化学株式会社 | 2023-02-02 | — | — | WO | disclosed |
| US-11565997-B2 | Method for preparing dicarbamate compounds from diamines and the catalyst thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2023-01-31 | — | — | US | disclosed |
| US-20220259380-A1 | PROCESS FOR THE DECOMPOSITION OF POLYETHER-POLYURETHANE | COVESTRO DEUTSCHLAND AG (DE) | 2022-08-18 | — | — | US | disclosed |
| EP-3630717-B1 | A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES | COUNCIL SCIENT IND RES (IN) | 2022-02-09 | — | — | EP | disclosed |
| US-20220002236-A1 | The method for preparing dicarbamate compounds from diamines and the catalyst thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2022-01-06 | — | — | US | disclosed |
| EP-3293173-B1 | METHOD FOR PRODUCING ISOCYANATE | ASAHI CHEMICAL IND (JP) | 2021-07-28 | — | — | EP | disclosed |
| EP-3625210-B1 | SILICA-BASED ZINC CATALYSTS. THEIR PREPARATION AND USE IN THE ALKOXYCARBONYLATION OF AMINES | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2021-06-23 | — | — | EP | disclosed |
| EP-3838892-A1 | METHOD FOR PRODUCING ISOCYANATE | Asahi Kasei Kabushiki Kaisha (JP) | 2021-06-23 | — | — | EP | disclosed |
| EP-2980066-B1 | METHOD FOR PRODUCING ISOCYANATE | ASAHI CHEMICAL IND (JP) | 2021-04-21 | — | — | EP | disclosed |
| EP-0014406-B1 | PROCESS FOR THE SEPARATION OF SELENIUM, SELENIUM COMPOUNDS, SULFUR AND/OR SULFUR COMPOUNDS FROM URETHANES CONTAINING THESE ELEMENTS AND/OR COMPOUNDS | BAYER AG (DE) | 1981-08-26 | — | — | EP | disclosed |
| EP-0028724-A1 | Process for preparing aryl isocyanates by thermal decomposition of aryl urethanes | BASF Aktiengesellschaft (DE) | 1981-05-20 | — | — | EP | disclosed |
| EP-0028338-A2 | Process for preparing aromatic di- and/or polyisocyanates | BASF Aktiengesellschaft (DE) | 1981-05-13 | — | — | EP | disclosed |
| US-4259511-A | Process for separating selenium, selenium compounds, sulfur and/or sulfur compounds from polyurethanes containing these elements and/or compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1981-03-31 | — | — | US | disclosed |
| EP-0016948-A1 | Process for preparing urethanes | BAYER AG (DE) | 1980-10-15 | — | — | EP | disclosed |
| EP-0014406-A1 | Process for the separation of selenium, selenium compounds, sulfur and/or sulfur compounds from urethanes containing these elements and/or compounds | BAYER AG (DE) | 1980-08-20 | — | — | EP | disclosed |
| US-4081472-A | CATALYTIC, FROM A CARBAMATE | MITSUI TOATSU CHEMICALS INC. (JA) | 1978-03-28 | — | — | US | disclosed |
| US-4069240-A | GROUP 8 METAL CATALYST | UNIROYAL, INC. (US) | 1978-01-17 | — | — | US | disclosed |
| US-3962302-A | Production of isocyanates from esters of carbamic acids (urethanes) | ATLANTIC RICHFIELD COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11565997-B2 | Method for preparing dicarbamate compounds from diamines and the catalyst thereof | AOC1, PPOX, SMOX | ALDH1A1 329/4885MAPK1 4093/4885LMNA 3789/4885 |
| US-20220002236-A1 | The method for preparing dicarbamate compounds from diamines and the catalyst thereof | AOC1, DDO, PPOX | ALDH1A1 372/4885MAPK1 4240/4885LMNA 3912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.