Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27616510 | 0.71 | CYP1A2 (0.56) | CYP1A2KDM4EGAAL3MBTL1NCF1 | |
| SCHEMBL4565139 | 0.68 | TP53 (0.52) | CYP1A2KDM4EGAAL3MBTL1NCF1 | |
| SCHEMBL2384919 | 0.66 | ALDH1A1 (0.51) | CYP1A2KDM4EGAAL3MBTL1NCF1 | |
| SCHEMBL10863962 | 0.66 | L3MBTL1 (0.61) | KDM4EGAAL3MBTL1NCF1ACHE | |
| SCHEMBL4564979 | 0.65 | L3MBTL1 (0.50) | KDM4EGAAL3MBTL1NCF1ACHE | |
| SCHEMBL7905729 | 0.63 | PDE10A (0.51) | CYP1A2KDM4EGAAL3MBTL1NCF1 | |
| SCHEMBL19583344 | 0.63 | POLB (0.55) | CYP1A2KDM4EGAAL3MBTL1NCF1 | |
| SCHEMBL14393692 | 0.63 | L3MBTL1 (0.69) | CYP1A2KDM4EGAAL3MBTL1NCF1 | |
| SCHEMBL13349812 | 0.62 | ALDH1A1 (0.43) | CYP1A2KDM4EGAAL3MBTL1TSHR | |
| SCHEMBL8264291 | 0.62 | LTB4R (0.49) | CYP1A2KDM4EGAANCF1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395564-A1 | QUINOLINE DERIVATIVES AS LIGANDS FOR THE NEUROPEPTIDE Y RECEPTOR | F. HOFFMANN-LA ROCHE AG (CH) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002094789-A1 | QUINOLINE DERIVATIVES AS LIGANDS FOR THE NEUROPEPTIDE Y RECEPTOR | F. HOFFMANN-LA ROCHE AG (CH) | 2002-11-28 | — | — | WO | disclosed |