SCHEMBL716935

SCHEMBL716935

BrCCCCOCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
TDP1 Q9NUW8 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
HRH4 Q9H3N8 1/20 0.46
HRH3 Q9Y5N1 1/20 0.46
NAAA Q02083 3/20 0.43
IDO1 P14902 1/20 0.41
GBA1 P04062 2/20 0.41
UGCG Q16739 2/20 0.41
GBA2 Q9HCG7 2/20 0.41
EPHX2 P34913 1/20 0.41
LTA4H P09960 1/20 0.41
TRPA1 O75762 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TEAD3 Q99594 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1309167 0.98 L3MBTL1 (0.54) TSHRTDP1L3MBTL1HRH4HRH3
SCHEMBL850609 0.98 L3MBTL1 (0.54) TSHRTDP1L3MBTL1HRH4HRH3
SCHEMBL879887 0.98 L3MBTL1 (0.54) TSHRTDP1L3MBTL1HRH4HRH3
SCHEMBL5619569 0.98 L3MBTL1 (0.54) TSHRTDP1L3MBTL1HRH4HRH3
SCHEMBL4229986 0.98 L3MBTL1 (0.54) TSHRTDP1L3MBTL1HRH4HRH3
SCHEMBL580258 0.98 L3MBTL1 (0.54) TSHRTDP1L3MBTL1HRH4HRH3
SCHEMBL7564811 0.98 L3MBTL1 (0.54) TSHRTDP1L3MBTL1HRH4HRH3
SCHEMBL517888 0.98 L3MBTL1 (0.54) TSHRTDP1L3MBTL1HRH4HRH3
SCHEMBL31490075 0.98 L3MBTL1 (0.54) TSHRTDP1L3MBTL1HRH4HRH3
SCHEMBL581027 0.98 L3MBTL1 (0.54) TSHRTDP1L3MBTL1HRH4HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 394 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250361248-A1 PROTAC COMPOUND WITH CYCLOPHILIN A DEGRADATION ACTIVITY, PREPARATION METHOD THEREFOR, AND USE THEREOF Shenzhen Bay Laboratory (CN) 2025-11-27 US claimed
WO-2024031965-A1 PROTAC COMPOUND WITH CYCLOPHILIN A DEGRADATION ACTIVITY, PREPARATION METHOD THEREFOR, AND USE THEREOF 深圳湾实验室 2024-02-15 WO claimed
CN-115028679-B PROTAC compound with Cyclophilin A degradation activity and preparation method and application thereof 深圳湾实验室 2022-11-15 CN claimed
CN-115028679-A PROTAC compound with Cyclophilin A degradation activity and preparation method and application thereof 深圳湾实验室 2022-09-09 CN claimed
CN-110642682-A Synthesis method of 5-oxaazelaic acid 上海吉奉生物科技有限公司 2020-01-03 CN claimed
US-20180194713-A1 PROCESSES AND INTERMEDIATES FOR PREPARING alpha,omega-DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS GEMPHIRE THERAPEUTICS INC. 2018-07-12 US claimed
EP-4743465-A1 BICYCLIC MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. Hoffmann-La Roche AG (CH) 2026-05-20 EP disclosed
EP-4159727-B1 INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN MORPHIC THERAPEUTIC INC (US) 2026-04-08 EP disclosed
US-20260041671-A1 BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE ARVINAS OPERATIONS INC (US) 2026-02-12 US disclosed
US-12539292-B2 BRM targeting compounds and associated methods of use ARVINAS OPERATIONS, INC. (US) 2026-02-03 US disclosed
US-20260001846-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS SERVIER LAB (FR) 2026-01-01 US disclosed
EP-4658636-A1 LIPID COMPOUNDS AND USES THEREOF Pfizer Inc. (US) 2025-12-10 EP disclosed
US-20250367129-A1 Lipid Compounds and Uses Thereof PFIZER (US) 2025-12-04 US disclosed
US-4777184-A ANTICOAGULANT, ANTIULCER AGENT SANKYO COMPANY LIMITED (JP) 1988-10-11 US disclosed
EP-0215401-A2 Method and composition for determining glycosylated hemoglobin as well as compounds suited therefor and methods for their preparation Roche Diagnostics GmbH (DE) 1987-03-25 EP disclosed
US-4649219-A CROSSLINKERS, ADHESIVES, PAINTS MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1987-03-10 US disclosed
US-4426526-A HISTAMINE ANTAGONISTS, ANTIINFLAMMATORY, ANTISECRETORY SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1984-01-17 US disclosed
US-4264608-A HISTAMINE ANTAGONISTS SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1981-04-28 US disclosed
US-4156727-A ANTIHISTAMINES SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1979-05-29 US disclosed
US-4154838-A ANTIHISTAMINE SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1979-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180194713-A1 PROCESSES AND INTERMEDIATES FOR PREPARING alpha,omega-DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS DGKI, DGKA, SQLE TSHR 3661/4885TDP1 3260/4885L3MBTL1 4881/4885
US-20250361248-A1 PROTAC COMPOUND WITH CYCLOPHILIN A DEGRADATION ACTIVITY, PREPARATION METHOD THEREFOR, AND USE THEREOF PPIA, PPIG, PPIF TSHR 4333/4885TDP1 3463/4885L3MBTL1 4638/4885
US-12539292-B2 BRM targeting compounds and associated methods of use ADRM1, SUMO2, BAZ1A TSHR 1630/4885TDP1 2586/4885L3MBTL1 666/4885
US-20260001846-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS BCL2, BCL2A1, BAX TSHR 3129/4885TDP1 2093/4885L3MBTL1 1235/4885
US-20260041671-A1 BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE ADRM1, VHL, BAZ1A TSHR 1673/4885TDP1 1739/4885L3MBTL1 317/4885
US-20250367129-A1 Lipid Compounds and Uses Thereof POLN, PHOSPHO1, NPC1 TSHR 3471/4885TDP1 1138/4885L3MBTL1 174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.