Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCER2 | P06734 | 4/20 | 0.56 |
| ▸ | MMP9 | P14780 | 9/20 | 0.52 |
| ▸ | MMP8 | P22894 | 6/20 | 0.52 |
| ▸ | MMP1 | P03956 | 15/20 | 0.51 |
| ▸ | MMP3 | P08254 | 11/20 | 0.51 |
| ▸ | MMP2 | P08253 | 7/20 | 0.51 |
| ▸ | MMP7 | P09237 | 3/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7173722 | 0.89 | FCER2 (0.57) | FCER2MMP9MMP8MMP1MMP3 | |
| SCHEMBL7177453 | 0.88 | MMP3 (0.55) | FCER2MMP9MMP8MMP1MMP3 | |
| SCHEMBL7170036 | 0.86 | MMP2 (0.57) | MMP9MMP8MMP1MMP3MMP2 | |
| SCHEMBL7173324 | 0.85 | SCN9A (0.43) | FCER2MMP9MMP8MMP1MMP3 | |
| SCHEMBL7177458 | 0.82 | MMP8 (0.52) | MMP8MMP1MMP3 | |
| SCHEMBL7170096 | 0.81 | FCER2 (0.50) | FCER2MMP9MMP8MMP1MMP3 | |
| SCHEMBL7172633 | 0.78 | FCER2 (0.41) | FCER2MMP9MMP8MMP1MMP3 | |
| SCHEMBL6852364 | 0.77 | FCER2 (0.81) | FCER2MMP9MMP8MMP1MMP3 | |
| SCHEMBL7178513 | 0.76 | MMP1 (0.44) | FCER2MMP9MMP8MMP1MMP3 | |
| SCHEMBL7178504 | 0.75 | MMP3 (0.45) | FCER2MMP9MMP1MMP3MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576628-B1 | Matrix metalloprotease inhibitors; arthritis, corneal ulcers, arteriosclerosis | ROCHE DIAGNOSTICS GMBH (DE) | 2003-06-10 | — | — | US | disclosed |
| EP-1005449-B1 | 3-ARYL-SUCCINAMIDO-HYDROXAMIC ACIDS, METHODS FOR PRODUCING SAID ACIDS AND MEDICAMENTS CONTAINING THE SAME | ROCHE DIAGNOSTICS GMBH (DE) | 2002-10-30 | — | — | EP | disclosed |
| EP-0897908-A1 | 3-Aryl-succinamido-hydroxamic acids, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1999-02-24 | — | — | EP | disclosed |