Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCER2 | P06734 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 6/20 | 0.40 |
| ▸ | MMP3 | P08254 | 5/20 | 0.40 |
| ▸ | MMP1 | P03956 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 6/20 | 0.39 |
| ▸ | TNF | P01375 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7170096 | 0.91 | FCER2 (0.50) | FCER2MMP2MMP3MMP1SMN1; SMN2 | |
| SCHEMBL7175105 | 0.90 | FCER2 (0.40) | FCER2MMP2MMP3MMP1ADAM17 | |
| SCHEMBL7176308 | 0.87 | MMP1 (0.46) | MMP2MMP3MMP1SMN1; SMN2HPGD | |
| SCHEMBL7172616 | 0.84 | MMP3 (0.46) | FCER2MMP2MMP3MMP1SMN1; SMN2 | |
| SCHEMBL7173680 | 0.84 | ALDH1A1 (0.41) | MMP2SMN1; SMN2HPGDMMP9MMP8 | |
| SCHEMBL7174311 | 0.82 | MMP3 (0.48) | MMP3MMP1MMP9 | |
| SCHEMBL7174032 | 0.78 | ADAM17 (0.50) | FCER2MMP2MMP3MMP1ADAM17 | |
| SCHEMBL7170101 | 0.78 | FCER2 (0.56) | FCER2MMP2MMP3MMP1ADAM17 | |
| SCHEMBL7172637 | 0.78 | SMN1; SMN2 (0.42) | MMP2MMP3MMP1SMN1; SMN2MMP13 | |
| SCHEMBL7172740 | 0.78 | MMP3 (0.52) | FCER2MMP2MMP3MMP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576628-B1 | Matrix metalloprotease inhibitors; arthritis, corneal ulcers, arteriosclerosis | ROCHE DIAGNOSTICS GMBH (DE) | 2003-06-10 | — | — | US | disclosed |
| EP-1005449-B1 | 3-ARYL-SUCCINAMIDO-HYDROXAMIC ACIDS, METHODS FOR PRODUCING SAID ACIDS AND MEDICAMENTS CONTAINING THE SAME | ROCHE DIAGNOSTICS GMBH (DE) | 2002-10-30 | — | — | EP | disclosed |
| EP-0897908-A1 | 3-Aryl-succinamido-hydroxamic acids, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1999-02-24 | — | — | EP | disclosed |