SCHEMBL717222

SCHEMBL717222

CCCCCCCCCCCC(CCCN)CCNCC(O)CN1CCN(CC(O)CNCCC(CCCN)CCCCCCCCCCC)CC1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 3/20 0.35
GNAO1 P09471 3/20 0.35
GNAI1 P63096 3/20 0.35
SPHK1 Q9NYA1 1/20 0.33
LMNA P02545 1/20 0.33
OPRL1 P41146 1/20 0.32
ALDH1A1 P00352 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
SIRT6 Q8N6T7 1/20 0.32
SIRT1 Q96EB6 1/20 0.32
HTT P42858 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ANPEP P15144 1/20 0.31
ERAP2 Q6P179 1/20 0.31
RRM1 P23921 1/20 0.31
KDM4E B2RXH2 1/20 0.30
USP2 O75604 1/20 0.30
ALOX15 P16050 1/20 0.30
DNM1 Q05193 3/20 0.30
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL716436 1.00 GNAI3 (0.35) GNAI3GNAO1GNAI1SPHK1LMNA
SCHEMBL716855 0.93 SLC6A5 (0.38) GNAI3GNAO1GNAI1MEN1KMT2A
SCHEMBL716853 0.93 SLC6A5 (0.38) GNAI3GNAO1GNAI1MEN1KMT2A
SCHEMBL720502 0.88 HTT (0.35) GNAI3GNAO1GNAI1LMNAOPRL1
SCHEMBL1477738 0.88 HTT (0.35) GNAI3GNAO1GNAI1LMNAOPRL1
SCHEMBL717828 0.82 FFAR1 (0.33) GNAI3GNAO1GNAI1HTT
SCHEMBL717827 0.82 FFAR1 (0.33) GNAI3GNAO1GNAI1HTT
SCHEMBL31215314 0.79 GNAI3 (0.38) GNAI3GNAO1GNAI1ALDH1A1L3MBTL1
SCHEMBL717870 0.79 GNAI3 (0.44) GNAI3GNAO1GNAI1USP2DNM1
SCHEMBL718213 0.79 GNAI3 (0.44) GNAI3GNAO1GNAI1USP2DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4710943-A2 TRANSFECTION COMPLEXES AND METHODS OF USING THE SAME Molecular Transfer, Inc. (US) 2026-03-18 EP claimed
EP-4565572-A1 LIPIDS FOR NUCLEIC ACID DELIVERY Life Technologies Corporation (US) 2025-06-11 EP claimed
US-20250154525-A1 PLANT VIRUS MOVEMENT PROTEINS AND METHODS OF USING SAME MOLECULAR TRANSFER, INC. 2025-05-15 US claimed
WO-2025034802-A2 AGENTS FOR DELIVERY OF NUCLEIC ACIDS Life Technologies Corporation (US) 2025-02-13 WO claimed
WO-2025034764-A1 LIPIDS FOR DELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS Life Technologies Corporation (US) 2025-02-13 WO claimed
CN-119137109-A Lipids for nucleic acid delivery 生命技术公司 2024-12-13 CN claimed
EP-4406963-A2 TRANSFECTION COMPLEXES AND METHODS OF USING THE SAME Molecular Transfer, Inc. (US) 2024-07-31 EP claimed
US-12037600-B2 Transfection complexes and methods of using the same MOLECULAR TRANSFER, INC. (US) 2024-07-16 US claimed
CN-118271422-A Transfection complexes and methods of use thereof 分子传递有限公司 2024-07-02 CN claimed
EP-4384508-A2 LIPIDS FOR NUCLEIC ACID DELIVERY Life Technologies Corporation (US) 2024-06-19 EP claimed
EP-2912045-A2 POLYCATIONIC METHYL PHOSPHOLIPIDS FOR IMPROVED DELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS Molecular Transfer, Inc. (US) 2015-09-02 EP claimed
WO-2014070687-A2 POLYCATIONIC METHYL PHOSPHOLIPIDS FOR IMPROVED DELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS MOLECULAR TRANSFER, INC. (US) 2014-05-08 WO claimed
EP-2696678-A1 AGENTS FOR IMPROVED DELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS Molecular Transfer, Inc. (US) 2014-02-19 EP claimed
WO-2013158127-A1 AGENTS FOR IMPROVED DELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS MOLECULAR TRANSFER, INC. (US) 2013-10-24 WO claimed
EP-2015780-B1 NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS MOLECULAR TRANSFER INC (US) 2012-12-12 EP claimed
WO-2012142622-A1 AGENTS FOR IMPROVED DELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS MOLECULAR TRANSFER, INC. (US) 2012-10-18 WO claimed
US-7915230-B2 Reagents for transfection of eukaryotic cells MOLECULAR TRANSFER, INC. (US) 2011-03-29 US claimed
US-20090023215-A1 Novel reagents for transfection of eukaryotic cells MOLECULAR TRANSFER (US) 2009-01-22 US claimed
EP-2015780-A2 NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS Molecular Transfer, Inc. (US) 2009-01-21 EP claimed
WO-2007130073-A2 NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS MOLECULAR TRANSFER, INC. (US) 2007-11-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250154525-A1 PLANT VIRUS MOVEMENT PROTEINS AND METHODS OF USING SAME HDLBP, PHAX, PLTP GNAI3 534/4885GNAO1 2667/4885GNAI1 1161/4885
US-20090023215-A1 Novel reagents for transfection of eukaryotic cells FUS, PHAX, PICALM GNAI3 1694/4885GNAO1 3683/4885GNAI1 1884/4885
US-12037600-B2 Transfection complexes and methods of using the same TIAL1, NPC1L1, LIPA GNAI3 1083/4885GNAO1 3364/4885GNAI1 1697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.