SCHEMBL718213

SCHEMBL718213

CCCCCCCCCCCCCC(CCCN)CCNCCCN1CCN(CCCNCCC(CCCN)CCCCCCCCCCCCC)CC1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 5/20 0.44
GNAO1 P09471 5/20 0.44
GNAI1 P63096 5/20 0.44
ACE2 Q9BYF1 1/20 0.42
USP2 O75604 1/20 0.39
RELA Q04206 4/20 0.35
PAOX Q6QHF9 1/20 0.33
DNM1 Q05193 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL717870 1.00 GNAI3 (0.44) GNAI3GNAO1GNAI1ACE2USP2
SCHEMBL719204 0.92 GNAI3 (0.39) GNAI3GNAO1GNAI1ACE2USP2
SCHEMBL719203 0.92 GNAI3 (0.39) GNAI3GNAO1GNAI1ACE2USP2
SCHEMBL28254554 0.91 GNAO1 (0.40) GNAI3GNAO1GNAI1ACE2USP2
SCHEMBL9322755 0.85 SCN5A (0.44) GNAI3GNAO1GNAI1USP2
SCHEMBL9322478 0.85 SCN5A (0.44) GNAI3GNAO1GNAI1USP2
SCHEMBL8703590 0.84 DNM1 (0.46) GNAI3GNAO1GNAI1RELADNM1
SCHEMBL716640 0.83 GNAI3 (0.42) GNAI3GNAO1GNAI1ACE2USP2
SCHEMBL718149 0.83 GNAI3 (0.42) GNAI3GNAO1GNAI1ACE2USP2
SCHEMBL717222 0.79 GNAI3 (0.35) GNAI3GNAO1GNAI1USP2DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4565572-A1 LIPIDS FOR NUCLEIC ACID DELIVERY Life Technologies Corporation (US) 2025-06-11 EP claimed
WO-2025034764-A1 LIPIDS FOR DELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS Life Technologies Corporation (US) 2025-02-13 WO claimed
WO-2025034802-A2 AGENTS FOR DELIVERY OF NUCLEIC ACIDS Life Technologies Corporation (US) 2025-02-13 WO claimed
EP-4384508-A2 LIPIDS FOR NUCLEIC ACID DELIVERY Life Technologies Corporation (US) 2024-06-19 EP claimed
WO-2024031051-A1 LIPIDS FOR NUCLEIC ACID DELIVERY Life Technologies Corporation (US) 2024-02-08 WO claimed
US-11866723-B2 Plant virus movement proteins and methods of using same Molecular Transfer Inc. (US) 2024-01-09 US claimed
EP-4175967-A2 TRINUCLEOTIDE CAP ANALOGS, PREPARATION AND USES THEREOF Life Technologies Corporation (US) 2023-05-10 EP claimed
WO-2023018990-A2 LIPIDS FOR NUCLEIC ACID DELIVERY Life Technologies Corporation (US) 2023-02-16 WO claimed
WO-2022006368-A2 TRINUCLEOTIDE CAP ANALOGS, PREPARATION AND USES THEREOF Life Technologies Corporation (US) 2022-01-06 WO claimed
US-10968240-B2 Polycationic methyl phospholipids for improved delivery of nucleic acids to eukaryotic cells MOLECULAR TRANSFER, INC. (US) 2021-04-06 US claimed
US-10155780-B2 Polycationic methyl phospholipids for improved delivery of nucleic acids to eukaryotic cells MOLECULAR TRANSFER, INC. (US) 2018-12-18 US claimed
US-20170029448-A1 POLYCATIONIC METHYL PHOSPHOLIPIDS FOR IMPROVEDDELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS MOLECULAR TRANSFER, INC. (US) 2017-02-02 US claimed
EP-2696678-A1 AGENTS FOR IMPROVED DELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS Molecular Transfer, Inc. (US) 2014-02-19 EP claimed
WO-2013158127-A1 AGENTS FOR IMPROVED DELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS MOLECULAR TRANSFER, INC. (US) 2013-10-24 WO claimed
EP-2015780-B1 NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS MOLECULAR TRANSFER INC (US) 2012-12-12 EP claimed
WO-2012142622-A1 AGENTS FOR IMPROVED DELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS MOLECULAR TRANSFER, INC. (US) 2012-10-18 WO claimed
US-7915230-B2 Reagents for transfection of eukaryotic cells MOLECULAR TRANSFER, INC. (US) 2011-03-29 US claimed
US-20090023215-A1 Novel reagents for transfection of eukaryotic cells MOLECULAR TRANSFER (US) 2009-01-22 US claimed
EP-4710943-A2 TRANSFECTION COMPLEXES AND METHODS OF USING THE SAME Molecular Transfer, Inc. (US) 2026-03-18 EP disclosed
WO-2007130073-A2 NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS MOLECULAR TRANSFER, INC. (US) 2007-11-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11866723-B2 Plant virus movement proteins and methods of using same HDLBP, PHAX, PLTP GNAI3 534/4885GNAO1 2667/4885GNAI1 1161/4885
US-10968240-B2 Polycationic methyl phospholipids for improved delivery of nucleic acids to eukaryotic cells PHOSPHO1, MBOAT7, PLTP GNAI3 1825/4885GNAO1 3482/4885GNAI1 1876/4885
US-10155780-B2 Polycationic methyl phospholipids for improved delivery of nucleic acids to eukaryotic cells PHOSPHO1, MBOAT7, PLTP GNAI3 1304/4885GNAO1 3143/4885GNAI1 1394/4885
US-20170029448-A1 POLYCATIONIC METHYL PHOSPHOLIPIDS FOR IMPROVEDDELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS PHOSPHO1, PLTP, MBOAT7 GNAI3 1147/4885GNAO1 3008/4885GNAI1 1404/4885
US-20090023215-A1 Novel reagents for transfection of eukaryotic cells FUS, PHAX, PICALM GNAI3 1694/4885GNAO1 3683/4885GNAI1 1884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.