SCHEMBL7174353

SCHEMBL7174353

COC(=O)/C(C)=C\C(=O)OC(=O)/C=C(/C)C(=O)OC

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
HCAR2 Q8TDS4 2/20 0.38
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7771274 0.87 HCAR2 (0.46) ALDH1A1HCAR2KEAP1NFE2L2MEN1
SCHEMBL5953576 0.87 HCAR2 (0.46) ALDH1A1HCAR2KEAP1NFE2L2MEN1
SCHEMBL774085 0.87 HCAR2 (0.46) ALDH1A1HCAR2KEAP1NFE2L2MEN1
Ammonia Solution, Strong SCHEMBL21219109 0.85 HCAR2 (0.43) ALDH1A1HCAR2KEAP1NFE2L2MEN1
Fluoride SCHEMBL28064852 0.85 HCAR2 (0.43) ALDH1A1HCAR2KEAP1NFE2L2MEN1
SCHEMBL9567808 0.85 HCAR2 (0.43) ALDH1A1HCAR2KEAP1NFE2L2MEN1
Ammonia Solution, Strong SCHEMBL6291855 0.85 HCAR2 (0.43) ALDH1A1HCAR2KEAP1NFE2L2MEN1
SCHEMBL7037263 0.79 ALDH1A1 (0.43) ALDH1A1HCAR2KEAP1NFE2L2
SCHEMBL14749991 0.79 ALDH1A1 (0.43) ALDH1A1HCAR2KEAP1NFE2L2
SCHEMBL28023754 0.79 ALDH1A1 (0.43) ALDH1A1HCAR2KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0996037-B1 Polyvinyl acetals having imido groups and use thereof in photosensitive compositions KODAK POLYCHROME GRAPHICS GMBH (DE) 2003-01-15 EP disclosed
US-6087066-A Polyvinyl acetals having imido groups and use thereof in photosensitive compositions KODAK POLYCHROME GRAPHICS LLC (US) 2000-07-11 US disclosed
EP-0996037-A2 Polyvinyl acetals having imido groups and use thereof in photosensitive compositions Kodak Polychrome Graphics GmbH (DE) 2000-04-26 EP disclosed
US-4611892-A Synthetic resin ophthalmic lens having a surface hard coat SEIKO EPSON CORPORATION (JP) 1986-09-16 US disclosed