SCHEMBL717592

SCHEMBL717592

CN(C(=O)CS)N(C)C(=O)CS

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
HSD17B10 Q99714 1/20 0.36
PHF8 Q9UPP1 1/20 0.36
KDM2A Q9Y2K7 1/20 0.36
ALDH1A1 P00352 2/20 0.32
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3905538 0.80
Hydrochloric Acid SCHEMBL10683777 0.78
SCHEMBL7522331 0.75 TSHR (0.33) TSHRHSD17B10PHF8KDM2A
SCHEMBL6703395 0.73
SCHEMBL15177751 0.71
SCHEMBL20220993 0.69 ALDH1A1 (0.36) ALDH1A1
SCHEMBL21765845 0.69 ALDH1A1 (0.41) TSHRHSD17B10PHF8KDM2AALDH1A1
SCHEMBL3905585 0.69
SCHEMBL22981787 0.68 CA1 (0.38)
SCHEMBL11704882 0.68 KMT2A (0.42) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4619408-A1 THE SYNTHESIS OF OMAPATRILAT Endothelium Scanning Nanotechnology Limited (AU) 2025-09-24 EP claimed
WO-2024103123-A1 THE SYNTHESIS OF OMAPATRILAT Endothelium Scanning Nanotechnology Limited (AU) 2024-05-23 WO claimed
CN-117860893-A Application of disulfide reducer in preparation of medicines for treating and preventing IgA nephropathy 深圳市陆为生物技术有限公司 2024-04-12 CN claimed
US-20240076553-A1 NONIONIC, REDOX-CLEAVABLE SURFACTANT FOR MASS SPECTROMETRY-BASED PROTEOMICS AND STRUCTURAL BIOLOGICAL APPLICATIONS WISCONSIN ALUMNI RESEARCH FOUNDATION 2024-03-07 US claimed
EP-1532965-B1 Cosmetic composition based on a cosmetical active ingredient and an gel comprising at least one reticulated network of reticulated polymer particles. OREAL (FR) 2007-08-22 EP claimed
EP-1352630-B1 Metallic shaping process which imparts cosmetic properties similar to shampooing to keratinous fibres OREAL (FR) 2006-03-01 EP claimed
US-20050186165-A1 Cosmetic composition based on a cosmetically active compound and a gel comprising at least one crosslinked network of crosslinked polymer particles L'OREAL S.A. (FR) 2005-08-25 US claimed
EP-1532965-A1 Cosmetic composition comprising a cosmetical active ingredient and at least one reticulated network of reticulated polymer particles L'OREAL (FR) 2005-05-25 EP claimed
US-20030223944-A1 Metallic coating process for giving keratin fibres shampoo-remanent cosmetic properties L'OREAL (FR) 2003-12-04 US claimed
EP-1352630-A2 Metallic shaping process which imparts cosmetic properties similar to shampooing to keratinous fibres L'OREAL (FR) 2003-10-15 EP claimed
US-12551555-B2 Compositions and methods for potentiating immune activity KUMQUAT BIOSCIENCES INC. (US) 2026-02-17 US disclosed
US-12522819-B2 Systems and methods for determining nucleic acids PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2026-01-13 US disclosed
US-12522820-B2 Systems and methods for determining nucleic acids PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2026-01-13 US disclosed
US-12473546-B2 Systems and methods for determining nucleic acids PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2025-11-18 US disclosed
US-20250340573-A1 THE SYNTHESIS OF OMAPATRILAT ENDOTHELIUM SCANNING NANOTECHNOLOGY LTD (AU) 2025-11-06 US disclosed
WO-1998020156-A1 HYDROLASE BINDING ASSAY MERCK FROSST CANADA & CO. (CA) 1998-05-14 WO disclosed
US-5523215-A CULTURING HOST CELL EXPRESSING DESIRED PROTEIN IN MEDIUM CONTAINING COPPER IONS, DISRUPTING, INCUBATING INSOLUBLE FRACTION WITH CHAOTROPIC AGENT TO DISSOLVE CONTAMINANTS, SEPARATING, TREATING INSOLUBLE FRACTION WITH REDUCING AGENT CHIRON CORPORATION (US) 1996-06-04 US disclosed
US-5378813-A Reduction of disulfide bonds using 2,5-dimercaptotetramethyl adipamide PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1995-01-03 US disclosed
EP-0623141-A1 SELECTION OF BINDING-MOLECULES THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1994-11-09 EP disclosed
WO-1993014108-A1 SELECTION OF BINDING-MOLECULES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1993-07-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240076553-A1 NONIONIC, REDOX-CLEAVABLE SURFACTANT FOR MASS SPECTROMETRY-BASED PROTEOMICS AND STRUCTURAL BIOLOGICAL APPLICATIONS PTMS, SRMS, DSP TSHR 4725/4885HSD17B10 1836/4885PHF8 3937/4885
US-12551555-B2 Compositions and methods for potentiating immune activity PTPRCAP, PTPN2, PTPRC TSHR 431/4885HSD17B10 4252/4885PHF8 3725/4885
US-20250340573-A1 THE SYNTHESIS OF OMAPATRILAT PARP1, PDE7A, TBXAS1 TSHR 3809/4885HSD17B10 2422/4885PHF8 2822/4885
US-20050186165-A1 Cosmetic composition based on a cosmetically active compound and a gel comprising at least one crosslinked network of crosslinked polymer particles CUTA, SUCLG1, KAT7 TSHR 3342/4885HSD17B10 694/4885PHF8 123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.