Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7118926 | 0.79 | WDR5 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7128798 | 0.75 | HSD11B1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7128017 | 0.74 | WDR5 (0.33) | — | |
| Hydrochloric Acid SCHEMBL7124886 | 0.71 | L3MBTL1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7168687 | 0.67 | WDR5 (0.30) | — | |
| Hydrochloric Acid SCHEMBL7128801 | 0.66 | HSD11B1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL7634794 | 0.65 | NTRK1 (0.33) | — | |
| SCHEMBL7130927 | 0.64 | HSD11B1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL7119325 | 0.63 | NTRK1 (0.36) | — | |
| SCHEMBL7130923 | 0.63 | HSD11B1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030148877-A1 | Metallocenes and catalysts for olefin-polymerisation | BASELL TECHNOLOGY COMPANY BV (NL) | 2003-08-07 | — | — | US | disclosed |
| EP-0952978-B1 | METALLOCENES AND CATALYSTS FOR OLEFIN-POLYMERISATION | BASELL POLYOLEFINE GMBH (DE) | 2003-01-22 | — | — | EP | disclosed |
| EP-0952978-A1 | METALLOCENES AND CATALYSTS FOR OLEFIN-POLYMERISATION | Montell Technology Company bv (NL) | 1999-11-03 | — | — | EP | disclosed |
| WO-1999024446-A1 | METALLOCENES AND CATALYSTS FOR OLEFIN-POLYMERISATION | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1999-05-20 | — | — | WO | disclosed |