SCHEMBL7176302

SCHEMBL7176302

O=C(O)c1c(Cl)cc(-c2ccccc2)c2c1C(=O)OC2=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.43
FABP3 P05413 4/20 0.40
FABP4 P15090 4/20 0.40
PRKAB2 O43741 2/20 0.39
PRKAG1 P54619 2/20 0.39
PRKAA2 P54646 2/20 0.39
PRKAA1 Q13131 2/20 0.39
PRKAG3 Q9UGI9 2/20 0.39
PRKAG2 Q9UGJ0 2/20 0.39
PRKAB1 Q9Y478 2/20 0.39
TTR P02766 1/20 0.39
AKR1C2 P52895 1/20 0.38
AKR1C1 Q04828 1/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
KDM4E B2RXH2 1/20 0.38
CTRC Q99895 2/20 0.38
HNF4A P41235 1/20 0.38
FABP5 Q01469 2/20 0.37
CYP2A6 P11509 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL247392 0.82 HNF4A (0.46) CHEK1FABP3FABP4AKR1C2AKR1C1
Biphenyl SCHEMBL5672703 0.79 PTPN1 (0.45) CHEK1FABP3FABP4PRKAB2PRKAG1
SCHEMBL28618774 0.75 CHEK1 (0.39) CHEK1FABP3FABP4KMT2AMEN1
SCHEMBL8221235 0.75 DPP4 (0.46) FABP3FABP4TTRKMT2AMEN1
SCHEMBL9813468 0.74 ACMSD (0.46) CHEK1HNF4AHDAC4HDAC2HDAC8
SCHEMBL9423374 0.73 TTR (0.44) CHEK1TTRKMT2AMEN1KDM4E
SCHEMBL7189911 0.73 NPSR1 (0.40) KDM4E
SCHEMBL28633398 0.73 PRKAB2 (0.43) FABP3FABP4PRKAB2PRKAG1PRKAA2
SCHEMBL15064384 0.72 MAPT (0.43) CHEK1FABP3FABP4KMT2AMEN1
SCHEMBL4802119 0.71 HNF4A (0.49) CHEK1FABP3FABP4AKR1C2AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6638631-B2 Stress relieving films comprising crosslinked mixtures of polysiloxanes, polyimides, polyamideimides copolymers and/or polyamides used as interfaces for semiconductors or printed circuits HITACHI, LTD. (JP) 2003-10-28 US disclosed
US-6638352-B2 For use in printed circuit boards; semiconductors HITACHI, LTD. (JP) 2003-10-28 US disclosed
US-20030047351-A1 Stress relieving films comprising crosslinked mixtures of polysiloxanes, polyimides, polyamideimides copolymers and/or polyamides used as interfaces for semiconductors or printed circuits SATSU YUICHI (JP) 2003-03-13 US disclosed
US-20030049193-A1 For use in printed circuit boards; semiconductors HITACHI,L TD (JP) 2003-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030049193-A1 For use in printed circuit boards; semiconductors ASIC1, ASIC3, RIOK2 CHEK1 1438/4885FABP3 4791/4885FABP4 4612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.