SCHEMBL718047

SCHEMBL718047

O=C1CCCC(=O)N1c1ccc2ccc3cccc4ccc1c2c34

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.43
KDM4E B2RXH2 4/20 0.43
KMT2A Q03164 3/20 0.43
HPGD P15428 6/20 0.39
HSD17B10 Q99714 4/20 0.39
TDP1 Q9NUW8 2/20 0.39
CYP3A4 P08684 2/20 0.39
TSHR P16473 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
POLB P06746 3/20 0.37
APEX1 P27695 1/20 0.37
CASP6 P55212 1/20 0.37
CTDSP1 Q9GZU7 1/20 0.37
CYP1A2 P05177 4/20 0.37
ERBB2 P04626 1/20 0.37
FYN P06241 1/20 0.37
MAOA P21397 1/20 0.37
ACHE P22303 1/20 0.37
AHR P35869 1/20 0.37
CYP1A1 P04798 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3263559 0.93 ALDH1A1 (0.45) ALDH1A1KDM4EKMT2AHPGDHSD17B10
Butyric Acid SCHEMBL1284593 0.79 KMT2A (0.47) ALDH1A1KDM4EKMT2AHPGDHSD17B10
SCHEMBL21928 0.77 TLR9 (0.47) ALDH1A1KDM4EKMT2AHPGDHSD17B10
SCHEMBL29400184 0.77 TLR9 (0.47) ALDH1A1KDM4EKMT2AHPGDHSD17B10
SCHEMBL29634180 0.77 TLR9 (0.47) ALDH1A1KDM4EKMT2AHPGDHSD17B10
SCHEMBL718741 0.77 POLB (0.58) ALDH1A1KDM4EKMT2AHPGDHSD17B10
SCHEMBL9151931 0.74 DDAH1 (0.41) DDAH1
SCHEMBL719850 0.73 POLB (0.41) ALDH1A1KDM4EKMT2AHPGDHSD17B10
Acetonitrile SCHEMBL28436643 0.71 ALDH1A1 (0.41) ALDH1A1KDM4EKMT2AHPGDHSD17B10
SCHEMBL31248316 0.71 TSHR (0.54) ALDH1A1KMT2ATSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9150414-B2 Nanocomposite and dispersion comprising the same KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2015-10-06 US disclosed
US-20120053288-A1 NANOCOMPOSITE AND DISPERSION COMPRISING THE SAME KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2012-03-01 US disclosed