Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.45 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7181326 | 0.80 | LMNA (0.59) | CYP1A2GRM2GRM3SLC1A3SLC1A2 | |
| SCHEMBL1716855 | 0.80 | TRPA1 (0.56) | CYP1A2GRM2GRM3SLC1A3SLC1A2 | |
| SCHEMBL12392847 | 0.80 | CYP1A2 (0.47) | CYP1A2GRM2GRM3SLC1A3SLC1A2 | |
| SCHEMBL25129603 | 0.79 | TAAR1 (0.48) | CYP1A2GRM2GRM3SLC1A3SLC1A2 | |
| SCHEMBL12228633 | 0.79 | TRPA1 (0.54) | CYP1A2GRM2GRM3SLC1A3SLC1A2 | |
| SCHEMBL13418600 | 0.75 | APAF1 (0.45) | CYP1A2GRM2GRM3SLC1A3SLC1A2 | |
| SCHEMBL9310046 | 0.75 | LMNA (0.58) | CYP1A2GRM2GRM3SLC1A3SLC1A2 | |
| SCHEMBL17816146 | 0.74 | LMNA (0.52) | MEN1KMT2ALMNAPOLB | |
| SCHEMBL3898638 | 0.74 | LMNA (0.52) | MEN1KMT2ALMNAPOLB | |
| SCHEMBL29100390 | 0.73 | GRM2 (0.44) | CYP1A2GRM2GRM3SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295604-A1 | (E)-2-(p-Fluorophenethyl)-3-fluoroallylamine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-12-21 | — | — | EP | disclosed |