SCHEMBL7181900

SCHEMBL7181900

Nc1cccc(S(=O)(=O)c2cc(N)cc(Cl)c2)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.71
CA2 P00918 3/20 0.53
CA12 O43570 2/20 0.53
CA1 P00915 2/20 0.53
CA4 P22748 2/20 0.53
CA9 Q16790 2/20 0.53
CA14 Q9ULX7 1/20 0.53
ALDH1A1 P00352 2/20 0.52
TSHR P16473 1/20 0.52
HSD17B10 Q99714 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
F2 P00734 3/20 0.45
PRSS1 P07477 3/20 0.45
PRSS2 P07478 3/20 0.45
PRSS3 P35030 3/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ANXA2 P07355 1/20 0.44
S100A10 P60903 1/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2808682 0.87 CYP3A4 (0.55) LMNACA2CA12CA1CA4
SCHEMBL5561963 0.84 LMNA (1.00) LMNACA2CA12CA1CA4
SCHEMBL30544199 0.84 LMNA (1.00) LMNACA2CA12CA1CA4
SCHEMBL29635012 0.84 LMNA (1.00) LMNACA2CA12CA1CA4
SCHEMBL34546 0.84 LMNA (1.00) LMNACA2CA12CA1CA4
Benzene SCHEMBL27752989 0.82 LMNA (0.95) LMNACA2CA12CA1CA4
SCHEMBL324628 0.82 LMNA (0.95) LMNACA2CA12CA1CA4
SCHEMBL7183566 0.81 MEN1 (0.68) LMNACA2CA12CA1CA4
SCHEMBL1100221 0.81 LMNA (0.91) LMNACA2CA12CA1CA4
SCHEMBL1961367 0.81 LMNA (0.50) LMNACA2CA1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed