SCHEMBL7183566

SCHEMBL7183566

Nc1ccc(S(=O)(=O)c2cc(N)cc(Cl)c2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.68
KMT2A Q03164 1/20 0.68
HTR6 P50406 5/20 0.61
CYP3A4 P08684 3/20 0.61
TSHR P16473 3/20 0.61
LMNA P02545 2/20 0.61
MPO P05164 1/20 0.61
CYP2C9 P11712 1/20 0.61
ALDH1A1 P00352 3/20 0.53
PKM P14618 2/20 0.53
PRMT1 Q99873 2/20 0.51
MAPK1 P28482 1/20 0.50
TP53 P04637 1/20 0.44
CA12 O43570 1/20 0.43
USP2 O75604 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2808682 0.90 CYP3A4 (0.55) MEN1KMT2AHTR6CYP3A4TSHR
SCHEMBL7190058 0.82 CA1 (0.56) MEN1KMT2AHTR6CYP3A4TSHR
SCHEMBL7181900 0.81 LMNA (0.71) MEN1KMT2AHTR6CYP3A4TSHR
SCHEMBL2762404 0.81 MEN1 (1.00) MEN1KMT2AHTR6CYP3A4TSHR
SCHEMBL1958687 0.81 ALDH1A1 (0.67) MEN1KMT2AHTR6CYP3A4TSHR
SCHEMBL8866046 0.79 MEN1 (0.66) MEN1KMT2AHTR6CYP3A4TSHR
SCHEMBL7185389 0.79 HSD11B1 (0.51) MEN1KMT2AHTR6CYP3A4TSHR
SCHEMBL324893 0.78 HTR6 (1.00) MEN1KMT2AHTR6CYP3A4TSHR
Dapsone SCHEMBL1219599 0.78 HTR6 (1.00) MEN1KMT2AHTR6CYP3A4TSHR
Dapsone SCHEMBL21428 0.78 HTR6 (1.00) MEN1KMT2AHTR6CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed