Sugi Predict

Sugi Predict / Compounds / SCHEMBL7183639

SCHEMBL7183639

SCHEMBL7183639

O=C(c1ccccc1)c1c(Cl)cc(Cl)c([PH](=O)C(=O)c2c(Cl)cccc2Cl)c1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.39
▸ ATM Q13315 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ ALDH1A1 P00352 5/20 0.37
▸ LMNA P02545 2/20 0.37
▸ MAPT P10636 2/20 0.37
▸ GAA P10253 2/20 0.37
▸ KCNK3 O14649 1/20 0.36
▸ KCNK9 Q9NPC2 1/20 0.36
▸ TSHR P16473 2/20 0.36
▸ RORC P51449 1/20 0.35
▸ PBRM1 Q86U86 2/20 0.35
▸ VCAM1 P19320 1/20 0.34
▸ NPC1 O15118 1/20 0.34
▸ PKM P14618 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ NFKB1 P19838 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ NFKB2 Q00653 1/20 0.34
▸ RELA Q04206 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7174760 0.91 LMNA (0.39) L3MBTL1ATMTDP1ALDH1A1LMNA
SCHEMBL7189826 0.89 ALDH1A1 (0.37) L3MBTL1ATMTDP1ALDH1A1LMNA
SCHEMBL7174653 0.88 LMNA (0.38) L3MBTL1ATMTDP1ALDH1A1LMNA
SCHEMBL7190116 0.88 RAB9A (0.41) ALDH1A1LMNAMAPTKCNK3KCNK9
SCHEMBL7177549 0.85 MAPT (0.41) L3MBTL1ATMALDH1A1LMNAMAPT
SCHEMBL7175976 0.85 RORC (0.39) ALDH1A1LMNAMAPTKCNK3KCNK9
SCHEMBL7188750 0.84 MEN1 (0.39) ALDH1A1LMNAMAPTGAANPC1
SCHEMBL7180948 0.84 ALDH1A1 (0.40) L3MBTL1ATMTDP1ALDH1A1LMNA
SCHEMBL7182791 0.82 TP53 (0.34) ALDH1A1LMNAMAPTGAANPC1
SCHEMBL7189282 0.81 LMNA (0.34) L3MBTL1ATMTDP1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 L3MBTL1 302/4885ATM 2823/4885TDP1 4234/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 L3MBTL1 126/4885ATM 2935/4885TDP1 4275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.