Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7183938 | 0.83 | HNF4A (0.44) | HNF4ARXRAPTGS1PTGS2MAPT | |
| SCHEMBL7196167 | 0.78 | PTGS1 (0.34) | HNF4APTGS1PTGS2 | |
| SCHEMBL7183949 | 0.75 | HNF4A (0.48) | HNF4ARXRAPTGS1PTGS2MAPT | |
| SCHEMBL21750733 | 0.73 | HNF4A (0.44) | HNF4AMAPT | |
| SCHEMBL3998188 | 0.71 | CYP26A1 (0.49) | HNF4ARXRA | |
| SCHEMBL9868856 | 0.64 | RXRA (0.45) | HNF4ARXRAMAPT | |
| SCHEMBL30983206 | 0.64 | PGR (0.34) | HNF4AMAPT | |
| SCHEMBL5782886 | 0.63 | PTGS2 (0.35) | PTGS1PTGS2 | |
| SCHEMBL21750809 | 0.63 | RARA (0.47) | HNF4ARXRAMAPT | |
| SCHEMBL6444615 | 0.63 | ERN1 (0.36) | PTGS1PTGS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586460-B1 | Administering heterocyclic ethers or sulfides to induce apoptosis, cell differentiation and as anticarcinogenic agents | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY | 2003-07-01 | — | — | US | disclosed |