SCHEMBL7185563

SCHEMBL7185563

CCOC(=S)N(C)c1ccccc1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
LMNA P02545 2/20 0.45
POLB P06746 3/20 0.43
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
KDM4E B2RXH2 4/20 0.42
ALDH1A1 P00352 4/20 0.42
MAPT P10636 4/20 0.42
GAA P10253 3/20 0.42
HPGD P15428 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
GLA P06280 1/20 0.42
ABCC1 P33527 2/20 0.41
MASP2 O00187 1/20 0.41
HSD17B10 Q99714 1/20 0.41
PIN1 Q13526 1/20 0.40
NPC1 O15118 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7185633 0.84 TSHR (0.49) TSHRLMNAPOLBMEN1KMT2A
SCHEMBL7195416 0.82 TSHR (0.44) TSHRPOLBMEN1KMT2AALDH1A1
SCHEMBL13041531 0.79 POLB (0.51) TSHRLMNAPOLBKDM4EALDH1A1
SCHEMBL7196902 0.79 CA1 (0.46) TSHRLMNAPOLBMEN1KMT2A
SCHEMBL4276628 0.79 ALDH1A1 (0.49) TSHRLMNAPOLBKDM4EALDH1A1
SCHEMBL7183302 0.78 MEN1 (0.40) TSHRLMNAPOLBMEN1KMT2A
SCHEMBL7194413 0.76 ALDH1A1 (0.38) TSHRLMNAPOLBMEN1KMT2A
SCHEMBL7187711 0.75 WDR5 (0.44) POLBMEN1KMT2AKDM4EALDH1A1
SCHEMBL27816640 0.75 FAAH (0.50) TSHRLMNAMEN1KMT2AALDH1A1
SCHEMBL9059212 0.75 KDM4E (0.44) TSHRLMNAPOLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1304924-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS Bayer Aktiengesellschaft (DE) 2003-05-02 EP disclosed
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed
WO-2002005646-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS S.C. JOHNSON & SON, INC. (US) (US) 2002-01-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 TSHR 4831/4885LMNA 4522/4885POLB 3165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.