SCHEMBL718562

SCHEMBL718562

CC(C)(c1ccccc1)c1cccc(N)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.54
MAPK1 P28482 1/20 0.54
ESR1 P03372 2/20 0.50
ESR2 Q92731 2/20 0.50
CYP3A4 P08684 2/20 0.48
ALDH1A1 P00352 1/20 0.48
MAOA P21397 4/20 0.46
CASP1 P29466 1/20 0.46
RECQL P46063 1/20 0.46
CNR1 P21554 3/20 0.44
CNR2 P34972 3/20 0.44
MAOB P27338 4/20 0.42
CYP19A1 P11511 1/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
GFER P55789 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29408725 0.93 ESR1 (0.57) TSHRMAPK1ESR1ESR2CYP3A4
SCHEMBL1725375 0.93 ESR1 (0.57) TSHRMAPK1ESR1ESR2CYP3A4
SCHEMBL126640 0.93 ESR1 (0.57) TSHRMAPK1ESR1ESR2CYP3A4
SCHEMBL125232 0.93 TSHR (0.60) TSHRMAPK1ESR1ESR2CYP3A4
SCHEMBL31476400 0.93 TSHR (0.60) TSHRMAPK1ESR1ESR2CYP3A4
SCHEMBL29374282 0.93 TSHR (0.60) TSHRMAPK1ESR1ESR2CYP3A4
SCHEMBL203901 0.91 TSHR (0.58) TSHRMAPK1ESR1ESR2CYP3A4
SCHEMBL29408726 0.91 TSHR (0.58) TSHRMAPK1ESR1ESR2CYP3A4
Toluene SCHEMBL28848821 0.90 TSHR (0.48) TSHRMAPK1ESR1ESR2CYP3A4
SCHEMBL13385785 0.89 ESR1 (0.53) TSHRMAPK1ESR1ESR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023072799-A1 BORONIC AND NITROGENOUS HETEROCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-05-04 WO disclosed
US-20230006137-A1 POLYCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING POLYCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-01-05 US disclosed
US-20230006137-A1 POLYCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING POLYCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-01-05 US disclosed
EP-3257093-B1 ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS MERCK PATENT GMBH (DE) 2021-07-07 EP disclosed
CN-105278241-B Photosensitive thermosetting resin composition, dry film and printed wiring board 太阳油墨制造株式会社 2020-08-11 CN disclosed
CN-110475859-A The method for inhibiting neural stem cell differentiating method, the method for preparation neural stem cell and induced nerve stem cells to break up UBE INDUSTRIES 2019-11-19 CN disclosed
CN-109562201-A For treating the implantation material of bone injury site and the treatment method of kit and bone injury site 宇部兴产株式会社 2019-04-02 CN disclosed
CN-109563300-A Method for producing porous polyimide film and porous polyimide film produced by the method 宇部兴产株式会社 2019-04-02 CN disclosed
CN-109563465-A Cell culture apparatus and the cell culture processes for using the cell culture apparatus 宇部兴产株式会社 2019-04-02 CN disclosed
CN-109496231-A Cell culture apparatus and the cell culture processes for using it 宇部兴产株式会社 2019-03-19 CN disclosed
CN-101516616-A Heat-resistant film metal foil laminate and method for producing same UBE INDUSTRIES (JP) 2009-08-26 CN disclosed
CN-1608835-A Flexible metal foil laminated body NIPPON MEKTELON CO LTD (JP) 2005-04-27 CN disclosed
US-6835520-B2 Can prevent occurrence of nibbled images without any damage of the photoreceptor and the intermediate transfer body, whereby good image quality can be stably obtained for a long period of time FUJI XEROX CO., LTD. (JP) 2004-12-28 US disclosed
US-20030157420-A1 Apparatus for forming image FUJI XEROX CO. LTD. (JP) 2003-08-21 US disclosed
US-5959068-A LIQUID POLYIMIDE BASED ON AROMATIC DIAMINE MONOMERS AND 4,4'-MONOETHYLENE TRIMELLATE AND/OR BIS/4-DICARBOXYPHENYL/-SULFONE ON A HEAT-RESISTANT FILM; ADHERING PARTS AROUND LEADFRAMES MAKING UP SEMICONDUCTOR DEVICES, E.G LEAD PINS TOMOEGAWA PAPER CO., LTD. (JP) 1999-09-28 US disclosed
US-5891540-A POLYIMIDE TOMOEGAWA PAPER CO., LTD. (JP) 1999-04-06 US disclosed
US-5866250-A POLYIMIDE TOMOEGAWA PAPER CO., LTD. (JP) 1999-02-02 US disclosed
US-5863988-A OXIDATION RESISTANT CURABLE ADHESIVE COMPRISING A DISSOLVED ACRYLONITRILE-BUTADIENE COPOLYMER, A PHENOLIC RESIN, A DIAMINE, DIMALEIMIDE COMPOUND AND/OR A POLYSILOXANE; FREE FROM GENERATING GAS, CURING AT LOW TEMPERATURE TOMOEGAWA PAPER CO., LTD. (JP) 1999-01-26 US disclosed
US-5756650-A COMPOSITION COMPRISING POLYAMIC ACID, CURE ACCELERATOR SELECTED FROM GROUP CONSISTING OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AMINO ACID COMPOUND, AROMATIC COMPOUND HAVING TWO OR MORE HYDROXYL GROUPS KABUSHIKI KAISHA TOSHIBA (JP) 1998-05-26 US disclosed
US-5723571-A POLYIMIDESILOXANE COPOLYMERS TOMOEGAWA PAPER CO., LTD. (JP) 1998-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230006137-A1 POLYCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING POLYCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING ORGANIC LIGHT-EMITTING DEVICE PPOX, PKD1, OCIAD1 TSHR 4003/4885MAPK1 1272/4885ESR1 162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.