Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718257 | 1.00 | HTT (0.43) | HTTPLA2G1BPLA2G2AKCNH2SPHK1 | |
| SCHEMBL718599 | 0.91 | MEN1 (0.39) | HTTSPHK1KDM4EMAPK1CYP2D6 | |
| SCHEMBL16813073 | 0.91 | HTT (0.47) | HTTPLA2G1BPLA2G2AKCNH2KDM4E | |
| SCHEMBL19467362 | 0.85 | HTT (0.36) | HTTPLA2G1BPLA2G2A | |
| SCHEMBL721174 | 0.85 | MEN1 (0.42) | HTTSPHK1KDM4EMAPK1CYP2D6 | |
| SCHEMBL721173 | 0.85 | MEN1 (0.42) | HTTSPHK1KDM4EMAPK1CYP2D6 | |
| SCHEMBL22026425 | 0.84 | GGPS1 (0.44) | HTTPLA2G1BPLA2G2ACHRM2KDM4E | |
| SCHEMBL14619487 | 0.83 | PLA2G1B (0.35) | HTTPLA2G1BPLA2G2AKCNH2CACNA1F | |
| SCHEMBL7356304 | 0.83 | KDM4E (0.46) | HTTPLA2G1BPLA2G2AKDM4EMAPK1 | |
| SCHEMBL22354437 | 0.82 | PLA2G1B (0.47) | PLA2G1BPLA2G2AKCNH2SPHK1CACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565572-A1 | LIPIDS FOR NUCLEIC ACID DELIVERY | Life Technologies Corporation (US) | 2025-06-11 | — | — | EP | claimed |
| WO-2025034802-A2 | AGENTS FOR DELIVERY OF NUCLEIC ACIDS | Life Technologies Corporation (US) | 2025-02-13 | — | — | WO | claimed |
| WO-2025034764-A1 | LIPIDS FOR DELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS | Life Technologies Corporation (US) | 2025-02-13 | — | — | WO | claimed |
| CN-119137109-A | Lipids for nucleic acid delivery | 生命技术公司 | 2024-12-13 | — | — | CN | claimed |
| WO-2024031051-A1 | LIPIDS FOR NUCLEIC ACID DELIVERY | Life Technologies Corporation (US) | 2024-02-08 | — | — | WO | claimed |
| EP-4175967-A2 | TRINUCLEOTIDE CAP ANALOGS, PREPARATION AND USES THEREOF | Life Technologies Corporation (US) | 2023-05-10 | — | — | EP | claimed |
| WO-2022006368-A2 | TRINUCLEOTIDE CAP ANALOGS, PREPARATION AND USES THEREOF | Life Technologies Corporation (US) | 2022-01-06 | — | — | WO | claimed |
| US-10155780-B2 | Polycationic methyl phospholipids for improved delivery of nucleic acids to eukaryotic cells | MOLECULAR TRANSFER, INC. (US) | 2018-12-18 | — | — | US | claimed |
| US-20170029448-A1 | POLYCATIONIC METHYL PHOSPHOLIPIDS FOR IMPROVEDDELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS | MOLECULAR TRANSFER, INC. (US) | 2017-02-02 | — | — | US | claimed |
| EP-2912045-A2 | POLYCATIONIC METHYL PHOSPHOLIPIDS FOR IMPROVED DELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS | Molecular Transfer, Inc. (US) | 2015-09-02 | — | — | EP | claimed |
| WO-2014070687-A2 | POLYCATIONIC METHYL PHOSPHOLIPIDS FOR IMPROVED DELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS | MOLECULAR TRANSFER, INC. (US) | 2014-05-08 | — | — | WO | claimed |
| EP-2015780-B1 | NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS | MOLECULAR TRANSFER INC (US) | 2012-12-12 | — | — | EP | claimed |
| US-7915230-B2 | Reagents for transfection of eukaryotic cells | MOLECULAR TRANSFER, INC. (US) | 2011-03-29 | — | — | US | claimed |
| US-20090023215-A1 | Novel reagents for transfection of eukaryotic cells | MOLECULAR TRANSFER (US) | 2009-01-22 | — | — | US | claimed |
| EP-4710943-A2 | TRANSFECTION COMPLEXES AND METHODS OF USING THE SAME | Molecular Transfer, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| EP-4642434-A2 | LIPID COMPOSITIONS ON THE BASIS OF IONIZABLE LIPIDS, USE FOR DELIVERY TO IMMUNE CELLS | Life Technologies Corporation (US) | 2025-11-05 | — | — | EP | disclosed |
| US-20250333729-A1 | TRINUCLEOTIDE CAP ANALOGS, PREPARATION AND USES THEREOF | Life Technologies Corporation | 2025-10-30 | — | — | US | disclosed |
| US-20090023215-A1 | Novel reagents for transfection of eukaryotic cells | MOLECULAR TRANSFER (US) | 2009-01-22 | — | — | US | disclosed |
| EP-2015780-A2 | NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS | Molecular Transfer, Inc. (US) | 2009-01-21 | — | — | EP | disclosed |
| WO-2007130073-A2 | NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS | MOLECULAR TRANSFER, INC. (US) | 2007-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10155780-B2 | Polycationic methyl phospholipids for improved delivery of nucleic acids to eukaryotic cells | PHOSPHO1, MBOAT7, PLTP | HTT 1930/4885PLA2G1B 114/4885PLA2G2A 40/4885 |
| US-20170029448-A1 | POLYCATIONIC METHYL PHOSPHOLIPIDS FOR IMPROVEDDELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS | PHOSPHO1, PLTP, MBOAT7 | HTT 2665/4885PLA2G1B 64/4885PLA2G2A 48/4885 |
| US-20090023215-A1 | Novel reagents for transfection of eukaryotic cells | FUS, PHAX, PICALM | HTT 1075/4885PLA2G1B 1523/4885PLA2G2A 562/4885 |
| US-20250333729-A1 | TRINUCLEOTIDE CAP ANALOGS, PREPARATION AND USES THEREOF | RNGTT, RNMT, CPSF7 | HTT 773/4885PLA2G1B 2983/4885PLA2G2A 3394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.