⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854945 | 0.75 | CA12 (0.31) | — | |
| SCHEMBL9387950 | 0.72 | — | — | |
| SCHEMBL28496349 | 0.65 | MMP1 (0.34) | — | |
| SCHEMBL3350436 | 0.64 | PDE4A (0.46) | — | |
| SCHEMBL9854757 | 0.64 | PGD (0.32) | — | |
| SCHEMBL5488415 | 0.64 | — | — | |
| SCHEMBL8383247 | 0.61 | MMP2 (0.46) | — | |
| SCHEMBL71382 | 0.61 | PGK1 (0.36) | — | |
| SCHEMBL927824 | 0.59 | OR51E2 (0.46) | — | |
| SCHEMBL3469330 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129512-B2 | Using increased ribulose 1,5-bisphosphate carboxylase/oxygenase (Rubisco) activity as reporter function indicating regenerated photosynthetic and production processes in plants | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20080256666-A1 | METHODS OF IDENTIFYING AND CREATING RUBISCO LARGE SUBUNIT VARIANTS WITH IMPROVED RUBISCO ACTIVITY, COMPOSITIONS AND METHODS OF USE THEREOF | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2008-10-16 | — | — | US | disclosed |