Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.43 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.43 |
| ▸ | RPS17 | P08708 | 1/20 | 0.43 |
| ▸ | RPSA | P08865 | 1/20 | 0.43 |
| ▸ | RPS2 | P15880 | 1/20 | 0.43 |
| ▸ | RPL35A | P18077 | 1/20 | 0.43 |
| ▸ | RPL7 | P18124 | 1/20 | 0.43 |
| ▸ | RPL17 | P18621 | 1/20 | 0.43 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.43 |
| ▸ | RPS3 | P23396 | 1/20 | 0.43 |
| ▸ | RPS12 | P25398 | 1/20 | 0.43 |
| ▸ | RPL13 | P26373 | 1/20 | 0.43 |
| ▸ | RPL10 | P27635 | 1/20 | 0.43 |
| ▸ | RPL12 | P30050 | 1/20 | 0.43 |
| ▸ | RPL9; RPL9P7; RPL9P8; RPL9P9 | P32969 | 1/20 | 0.43 |
| ▸ | RPL22 | P35268 | 1/20 | 0.43 |
| ▸ | RPL4 | P36578 | 1/20 | 0.43 |
| ▸ | RPS19 | P39019 | 1/20 | 0.43 |
| ▸ | RPL3 | P39023 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7190060 | 0.92 | ESR1 (0.40) | FFAR1FFAR4APPNPC1RAB9A | |
| SCHEMBL7195351 | 0.87 | MAPT (0.47) | MMP3FFAR1FFAR4ALDH1A1KDM4E | |
| SCHEMBL7188049 | 0.86 | FFAR1 (0.56) | MMP3FFAR1FFAR4ALDH1A1NPC1 | |
| SCHEMBL7193824 | 0.82 | ESR1 (0.47) | MMP3FFAR1FFAR4ALDH1A1MAPT | |
| SCHEMBL7195408 | 0.79 | ESR1 (0.51) | NPC1ESR1ESR2MEN1KMT2A | |
| SCHEMBL7195102 | 0.79 | CYP4F2 (0.46) | FFAR1FFAR4ALDH1A1KDM4EMAPT | |
| SCHEMBL7189113 | 0.78 | FFAR1 (0.57) | FFAR1FFAR4 | |
| SCHEMBL7185068 | 0.78 | MAPT (0.46) | FFAR1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL8497554 | 0.78 | L3MBTL1 (0.51) | MMP3ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL7189999 | 0.77 | CYP4F2 (0.46) | FFAR1FFAR4ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835867-B1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 2003-12-03 | — | — | EP | claimed |