Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7189113 | 0.92 | FFAR1 (0.57) | FFAR1FFAR4AKR1B1SRD5A2 | |
| SCHEMBL7190482 | 0.90 | ESR1 (0.53) | FFAR1FFAR4AKR1B1SRD5A2 | |
| SCHEMBL7183920 | 0.89 | FFAR1 (0.50) | FFAR1FFAR4AKR1B1SRD5A2 | |
| SCHEMBL7187264 | 0.89 | FFAR1 (0.56) | FFAR1FFAR4AKR1B1SRD5A2 | |
| SCHEMBL7183632 | 0.89 | FFAR1 (0.52) | FFAR1FFAR4NPC1RAB9AALDH1A1 | |
| SCHEMBL7195351 | 0.87 | MAPT (0.47) | FFAR1FFAR4NPC1RAB9AMEN1 | |
| SCHEMBL7187431 | 0.86 | MMP3 (0.43) | FFAR1FFAR4NPC1RAB9AMEN1 | |
| SCHEMBL7188059 | 0.86 | ESR1 (0.55) | FFAR1FFAR4ALDH1A1 | |
| SCHEMBL7193824 | 0.85 | ESR1 (0.47) | FFAR1FFAR4NPC1RAB9AALDH1A1 | |
| SCHEMBL7187874 | 0.84 | ESR1 (0.55) | FFAR1FFAR4NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835867-B1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 2003-12-03 | — | — | EP | claimed |
| US-5916916-A | USEFUL AS SELECTIVE ESTROGEN RECEPTOR MODULATORS. | ELI LILLY AND COMPANY (US) | 1999-06-29 | — | — | US | claimed |
| EP-0835867-A1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | claimed |
| EP-0835867-B1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 2003-12-03 | — | — | EP | disclosed |
| US-5916916-A | USEFUL AS SELECTIVE ESTROGEN RECEPTOR MODULATORS. | ELI LILLY AND COMPANY (US) | 1999-06-29 | — | — | US | disclosed |
| EP-0835867-A1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |