Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4664225 | 0.84 | OPRL1 (0.49) | GRIN2BOPRM1OPRD1OPRK1HTR1A | |
| SCHEMBL4663525 | 0.80 | OPRK1 (0.49) | OPRM1OPRD1OPRK1SLC6A4SLC6A2 | |
| SCHEMBL4665572 | 0.73 | OPRL1 (0.47) | GRIN2BOPRM1OPRD1OPRK1HTR1A | |
| SCHEMBL4665942 | 0.70 | SMN1; SMN2 (0.38) | OPRM1OPRD1OPRK1SLC6A4SLC6A2 | |
| SCHEMBL4665533 | 0.69 | TRPA1 (0.38) | OPRM1SLC6A4DRD2DRD4SLC6A2 | |
| SCHEMBL5170874 | 0.69 | OPRM1 (0.39) | GRIN2BOPRM1OPRD1OPRK1HTR1A | |
| SCHEMBL5170803 | 0.68 | OPRM1 (0.39) | GRIN2BOPRM1OPRD1OPRK1HTR1A | |
| SCHEMBL4663394 | 0.67 | OPRK1 (0.53) | OPRM1OPRD1OPRK1SLC6A4SLC6A2 | |
| SCHEMBL4665743 | 0.67 | SLC6A4 (0.41) | OPRM1OPRD1OPRK1HTR1ASLC6A4 | |
| SCHEMBL4663720 | 0.67 | OPRK1 (0.60) | OPRM1OPRD1OPRK1SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1571140-B1 | C-substituted cyclohexylmethylamine derivatives | GRUENENTHAL GMBH (DE) | 2008-11-12 | — | — | EP | claimed |