Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22924512 | 0.81 | SIRT1 (0.55) | ALDH1A1DRD1POLBNPC1RAB9A | |
| SCHEMBL4122311 | 0.81 | ALDH1A1 (0.44) | ALDH1A1ALOX15POLBSMN1; SMN2CA12 | |
| SCHEMBL823696 | 0.77 | POLB (0.64) | ALDH1A1ALOX15POLBNPC1RAB9A | |
| SCHEMBL9815789 | 0.77 | ALDH1A1 (0.52) | ALDH1A1ALOX15POLBRAB9ACA12 | |
| SCHEMBL29378135 | 0.77 | POLB (0.64) | ALDH1A1ALOX15POLBNPC1RAB9A | |
| SCHEMBL28987559 | 0.77 | HSD17B10 (0.55) | ALDH1A1ALOX15POLBATMCA1 | |
| SCHEMBL30655797 | 0.75 | ALDH1A1 (0.50) | ALDH1A1ALOX15POLBNPC1RAB9A | |
| SCHEMBL464847 | 0.75 | ALDH1A1 (0.50) | ALDH1A1ALOX15POLBNPC1RAB9A | |
| SCHEMBL3440670 | 0.74 | HTT (0.51) | ALDH1A1ALOX15NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1448528 | 0.73 | ALDH1A1 (0.48) | ALDH1A1ALOX15POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6579663-B2 | Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-06-17 | — | — | US | disclosed |
| US-6399805-B2 | SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-06-04 | — | — | US | disclosed |