SCHEMBL823696

SCHEMBL823696

O=C(Cl)c1ccccc1SSc1ccccc1C(=O)Cl

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.64
ALDH1A1 P00352 3/20 0.52
ALOX15 P16050 2/20 0.52
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
CA9 Q16790 3/20 0.41
CA12 O43570 1/20 0.41
CA4 P22748 1/20 0.41
CA7 P43166 1/20 0.41
CYP1A2 P05177 1/20 0.39
SIRT1 Q96EB6 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
APOBEC3G Q9HC16 2/20 0.38
CETP P11597 2/20 0.37
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
RAB9A P51151 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29378135 1.00 POLB (0.64) POLBALDH1A1ALOX15CA1CA2
SCHEMBL9815789 0.86 ALDH1A1 (0.52) POLBALDH1A1ALOX15CA1CA2
SCHEMBL30655797 0.84 ALDH1A1 (0.50) POLBALDH1A1ALOX15CA1CA2
SCHEMBL464847 0.84 ALDH1A1 (0.50) POLBALDH1A1ALOX15CA1CA2
SCHEMBL3440670 0.82 HTT (0.51) ALDH1A1ALOX15MAPTMEN1KMT2A
SCHEMBL422 0.79 ALDH1A1 (0.67) POLBALDH1A1ALOX15CA1CA2
SCHEMBL11476180 0.79 SIRT1 (0.67) POLBALDH1A1ALOX15CA1CA2
SCHEMBL29380162 0.78 POLB (1.00) POLBALDH1A1ALOX15CA1CA2
SCHEMBL144989 0.78 POLB (1.00) POLBALDH1A1ALOX15CA1CA2
SCHEMBL7189083 0.77 ALDH1A1 (0.48) POLBALDH1A1ALOX15CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118240272-A Sponge for wiping automobile leather and preparation process thereof 江阴樱花梦家庭用品有限公司 2024-06-25 CN claimed
CN-113209364-B Polymer hydrogel with tissue light healing function and preparation and application thereof 四川大学 2022-02-08 CN claimed
CN-113209364-A Polymer hydrogel with tissue light healing function and preparation and application thereof 四川大学 2021-08-06 CN claimed
CN-111592634-B Photoreduction self-degradation polymer and preparation method and application thereof 四川大学 2021-04-09 CN claimed
CN-111592634-A Photoreduction self-degradation polymer and preparation method and application thereof 四川大学 2020-08-28 CN claimed
CN-111440102-A Preparation method of dithiodibenzoamide compound 大连凯飞化学股份有限公司 2020-07-24 CN claimed
CN-210410642-U High-efficiency catalytic synthesis reactor for 2, 2' -dithiodibenzoyl chloride 绍兴市上虞三维化工有限公司 2020-04-28 CN claimed
US-6350879-B1 ENZYME INHIBITORS COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-02-26 US claimed
EP-0874835-A1 METHOD OF MAKING (S-(R*,R*))-3-METHYL-2-(3-OXO-3H-BENZO(D)ISOTHIAZOL-2-YL)PENTANOIC ACID AND (S-(R*,R*)), L-2-(2-(2-(1-CARBOXY-2-METHYLBUTYLCARBAMOYL)PHENYLDISULFONYL)BENZOYL-AMINO)-3-METHYLPENTANOIC ACID WARNER-LAMBERT COMPANY (US) 1998-11-04 EP claimed
WO-1997022598-A1 METHOD OF MAKING (S-(R*,R*))-3-METHYL-2-(3-OXO-3H-BENZO(D)ISOTHIAZOL-2-YL)PENTANOIC ACID AND (S-(R*,R*)), L-2-(2-(2-(1-CARBOXY-2-METHYLBUTYLCARBAMOYL)PHENYLDISULFONYL)BENZOYL-AMINO)-3-METHYLPENTANOIC ACID WARNER-LAMBERT COMPANY (US) 1997-06-26 WO claimed
US-5342724-A Preparing polyester from diol and diacid wherein one of the monomers has disulfuide linkage, reacting polyester with unsaturated monomer to create addition polymer blocks linked by sulfide group from dislufide linkage EASTMAN KODAK COMPANY (US) 1994-08-30 US claimed
JP-58194860-A None JP disclosed
CN-118240272-A Sponge for wiping automobile leather and preparation process thereof 江阴樱花梦家庭用品有限公司 2024-06-25 CN disclosed
CN-118240272-A Sponge for wiping automobile leather and preparation process thereof 江阴樱花梦家庭用品有限公司 2024-06-25 CN disclosed
CN-115916463-A Microspheres containing polymerizable functional groups 株式会社德山 2023-04-04 CN disclosed
EP-0000254-A1 Antithrombotic 2-(gamma-(1-piperidinyl)propyl)1,2-benzisothiazol 3-one, its pharmaceutically acceptable acid addition salts, their preparation and their compositions BEECHAM GROUP PLC (GB) 1979-01-10 EP disclosed
US-4118232-A Photographic material containing sulphonic acid group containing disazo dyestuffs CIBA-GEIGY AG (CH) 1978-10-03 US disclosed
US-4113728-A ANTICOAGULANTS BEECHAM GROUP LIMITED (GB) 1978-09-12 US disclosed
US-4051123-A Sulfonic-acid-group containing disazo dyestuffs CIBA-GEIGY AG (CH) 1977-09-27 US disclosed
US-4042600-A Pyrolysis of 2-sulfochloride benzoates SCOTT PAPER COMPANY (US) 1977-08-16 US disclosed