Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30655797 | 1.00 | ALDH1A1 (0.50) | ALDH1A1ALOX15POLBCA12CA1 | |
| SCHEMBL823696 | 0.84 | POLB (0.64) | ALDH1A1ALOX15POLBCA12CA1 | |
| SCHEMBL29378135 | 0.84 | POLB (0.64) | ALDH1A1ALOX15POLBCA12CA1 | |
| SCHEMBL9815789 | 0.84 | ALDH1A1 (0.52) | ALDH1A1ALOX15POLBCA12CA1 | |
| SCHEMBL16534454 | 0.82 | POLB (0.68) | ALDH1A1ALOX15POLBCA12CA1 | |
| SCHEMBL3440670 | 0.80 | HTT (0.51) | ALDH1A1ALOX15RAB9ATSHRNPC1 | |
| SCHEMBL7418361 | 0.80 | SIRT1 (0.60) | ALDH1A1POLBSIRT1RAB9ATSHR | |
| SCHEMBL422 | 0.77 | ALDH1A1 (0.67) | ALDH1A1ALOX15POLBCA12CA1 | |
| SCHEMBL11476180 | 0.77 | SIRT1 (0.67) | ALDH1A1ALOX15POLBCA12CA1 | |
| SCHEMBL7189083 | 0.75 | ALDH1A1 (0.48) | ALDH1A1ALOX15POLBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113861162-A | Preparation process of photoinitiator 2-/4-isopropyl thioxanthone | 喆鹿(山东)新材料有限公司 | 2021-12-31 | — | — | CN | claimed |
| US-4101558-A | Process for preparing thioxanthones | THE SHERWIN-WILLIAMS COMPANY (US) | 1978-07-18 | — | — | US | claimed |
| CN-116964043-A | Type II photoinitiators | 阿科玛法国公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-113861162-A | Preparation process of photoinitiator 2-/4-isopropyl thioxanthone | 喆鹿(山东)新材料有限公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-113861162-A | Preparation process of photoinitiator 2-/4-isopropyl thioxanthone | 喆鹿(山东)新材料有限公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-107663182-B | Glutamine metabolism inhibitor compound | 杭州健昵福生物科技有限公司 | 2020-12-22 | — | — | CN | disclosed |
| US-10711002-B2 | Purine compounds and method for the treatment of cancer | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2020-07-14 | — | — | US | disclosed |
| US-20190119279-A1 | PURINE COMPOUNDS AND METHOD FOR THE TREATMENT OF CANCER | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2019-04-25 | — | — | US | disclosed |
| WO-2017181285-A1 | PURINE COMPOUNDS AND METHOD FOR THE TREATMENT OF CANCER | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2017-10-26 | — | — | WO | disclosed |
| US-9694086-B2 | HCV protease inhibitors and uses thereof | CELGENE CAR LLC (BM) | 2017-07-04 | — | — | US | disclosed |
| US-20160243249-A1 | HCV PROTEASE INHIBITORS AND USES THEREOF | CELGENE CAR LLC (BM) | 2016-08-25 | — | — | US | disclosed |
| US-5348946-A | Heteroanthracycline antitumor analogs | BIOCHEM IMMUNOSYSTEMS, INC. (CA) | 1994-09-20 | — | — | US | disclosed |
| WO-1994020479-A1 | N-(BETA-BRANCHED ALKYL)-1,2-BENZISOTHIAZOLIN-3-ONES, THEIR PREPARATION AND USE AS INDUSTRIAL BIOCIDES | ZENECA LIMITED (GB) | 1994-09-15 | — | — | WO | disclosed |
| EP-0502661-A2 | Heteroanthracycline anti-tumor analogues | BIOCHEM PHARMA INC. (CA) | 1992-09-09 | — | — | EP | disclosed |
| EP-0269339-A2 | Novel daunomycin and adriamycin sulfono and sulfoxo | ABI BIOTECHNOLOGY INC. (CA) | 1988-06-01 | — | — | EP | disclosed |
| EP-0141119-A2 | Sulfenamide derivatives, process for their preparation, and medicaments containing these compounds | LUDWIG HEUMANN & CO GMBH (DE) | 1985-05-15 | — | — | EP | disclosed |
| US-4399145-A | Lactams Compositions and pharmaceutical methods of use | GRUNENTHAL GMBH (DE) | 1983-08-16 | — | — | US | disclosed |
| EP-0054672-A1 | Lactam compounds, pharmaceutical preparations containing them, and processes for the preparation of these compounds and pharmaceutical preparations | Grünenthal GmbH (DE) | 1982-06-30 | — | — | EP | disclosed |
| US-4101558-A | Process for preparing thioxanthones | THE SHERWIN-WILLIAMS COMPANY (US) | 1978-07-18 | — | — | US | disclosed |
| US-4101558-A | Process for preparing thioxanthones | THE SHERWIN-WILLIAMS COMPANY (US) | 1978-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10711002-B2 | Purine compounds and method for the treatment of cancer | PNP, NUDT1, HPRT1 | ALDH1A1 236/4885ALOX15 2322/4885POLB 306/4885 |
| US-20160243249-A1 | HCV PROTEASE INHIBITORS AND USES THEREOF | PEPD, CTRL, CTSC | ALDH1A1 1344/4885ALOX15 1685/4885POLB 3055/4885 |
| US-20190119279-A1 | PURINE COMPOUNDS AND METHOD FOR THE TREATMENT OF CANCER | PNP, NUDT1, HPRT1 | ALDH1A1 236/4885ALOX15 2322/4885POLB 306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.