Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463254 | 1.00 | CTSS (0.34) | CTSSCTSKALDH1A1MEN1KMT2A | |
| SCHEMBL6468282 | 0.91 | MEN1 (0.32) | ALDH1A1MEN1KMT2APTPN1PTPN2 | |
| SCHEMBL6467283 | 0.91 | MEN1 (0.38) | CTSSCTSKALDH1A1MEN1KMT2A | |
| SCHEMBL7189139 | 0.83 | CTSS (0.45) | CTSSCTSKALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6466455 | 0.82 | SMN1; SMN2 (0.36) | ALDH1A1MEN1KMT2ALMNAHPGD | |
| SCHEMBL6462134 | 0.81 | SMN1; SMN2 (0.34) | MEN1KMT2ALMNATSHRPPARG | |
| SCHEMBL7049540 | 0.80 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ALMNATSHR | |
| Hydrochloric Acid SCHEMBL6462052 | 0.80 | CTSC (0.39) | MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL7189151 | 0.80 | CTSS (0.40) | CTSSCTSKALDH1A1MEN1KMT2A | |
| SCHEMBL7042866 | 0.78 | LMNA (0.32) | LMNAPTPN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |