Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.40 |
| ▸ | CTSK | P43235 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7189139 | 0.86 | CTSS (0.45) | CTSSCTSKCTSLCTSBMEN1 | |
| SCHEMBL6463256 | 0.82 | CTSS (0.38) | CTSSCTSKCYP3A4CTSLCTSB | |
| Hydrochloric Acid SCHEMBL6462052 | 0.80 | CTSC (0.39) | CYP3A4CTSBMEN1KMT2A | |
| SCHEMBL6463254 | 0.80 | CTSS (0.34) | CTSSCTSKMEN1ALDH1A1LMNA | |
| SCHEMBL7189147 | 0.80 | CTSS (0.34) | CTSSCTSKMEN1ALDH1A1LMNA | |
| SCHEMBL5731226 | 0.80 | CTSK (0.46) | CTSSCTSKMEN1ALDH1A1LMNA | |
| SCHEMBL5731227 | 0.80 | CTSK (0.46) | CTSSCTSKMEN1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6466455 | 0.76 | SMN1; SMN2 (0.36) | CYP3A4CTSBMEN1ALDH1A1LMNA | |
| SCHEMBL7045339 | 0.76 | CTSL (0.42) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6468282 | 0.73 | MEN1 (0.32) | CTSBMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |