Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7189147 | 0.91 | CTSS (0.34) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL6463254 | 0.91 | CTSS (0.34) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL6462134 | 0.90 | SMN1; SMN2 (0.34) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6466455 | 0.86 | SMN1; SMN2 (0.36) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6462052 | 0.82 | CTSC (0.39) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL6466197 | 0.81 | FAAH (0.36) | SMN1; SMN2FAAHCES1DAGLAPTPN2 | |
| SCHEMBL7466136 | 0.81 | FAAH (0.36) | SMN1; SMN2FAAHCES1DAGLAPTPN2 | |
| SCHEMBL6467283 | 0.80 | MEN1 (0.38) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7045339 | 0.78 | CTSL (0.42) | CTSB | |
| SCHEMBL6467033 | 0.78 | FAAH (0.36) | SMN1; SMN2NPC1RAB9AFAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | US | disclosed |
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | SERPINB1, CTRL, CTSZ | MEN1 4023/4885KMT2A 3705/4885SMN1; SMN2 4034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.