Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.42 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10600409 | 0.85 | NR3C1 (0.43) | NR3C1CYP19A1ARPGRNR3C2 | |
| SCHEMBL4826656 | 0.84 | NR3C1 (0.64) | NR3C1CYP19A1ARPGRNR3C2 | |
| SCHEMBL9470387 | 0.78 | ESR1 (0.46) | NR3C1CYP19A1ARPGRNR3C2 | |
| SCHEMBL14571254 | 0.76 | NR3C1 (0.64) | NR3C1CYP19A1SERPINA6ARPGR | |
| SCHEMBL8242650 | 0.76 | NR3C1 (0.64) | NR3C1CYP19A1SERPINA6ARPGR | |
| SCHEMBL10530695 | 0.73 | NR3C1 (0.55) | NR3C1CYP19A1ARPGRNR3C2 | |
| SCHEMBL4843294 | 0.73 | NR3C1 (0.42) | NR3C1CYP19A1SERPINA6ARPGR | |
| SCHEMBL11321023 | 0.72 | NFKB1 (0.41) | NR3C1CYP19A1ARPGRNR3C2 | |
| SCHEMBL6390866 | 0.72 | ALDH1A1 (0.53) | NR3C1CYP19A1SERPINA6ARPGR | |
| SCHEMBL4978357 | 0.72 | NR3C1 (0.61) | NR3C1CYP19A1ARPGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586591-B2 | Removing an 11 alpha-leaving group from a 20-spiroxane derivative | G.D. SEARLE & CO. | 2003-07-01 | — | — | US | disclosed |
| US-20020042507-A1 | Process for preparation of 9,11-epoxy steroids and intermediates useful therein | NG JOHN S (US) | 2002-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020042507-A1 | Process for preparation of 9,11-epoxy steroids and intermediates useful therein | CYP4A11, HSD11B1, DHCR7 | NR3C1 42/4885CYP19A1 161/4885SERPINA6 3168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.