Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6712491 | 0.93 | MMP9 (0.48) | MMP9KMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7174955 | 0.92 | KMT2A (0.42) | MMP9KMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6709350 | 0.91 | ALDH1A1 (0.46) | MMP9KMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7538007 | 0.90 | MMP9 (0.46) | MMP9KMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6712429 | 0.88 | LMNA (0.40) | MMP9KMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7421577 | 0.86 | MMP9 (0.37) | MMP9KMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7320647 | 0.85 | THRB (0.39) | MMP9KMT2ASMN1; SMN2MEN1MAPK1 | |
| SCHEMBL7319356 | 0.85 | CA1 (0.37) | MMP9KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL6714601 | 0.84 | ALDH1A1 (0.45) | KMT2AALDH1A1SMN1; SMN2MEN1RAB9A | |
| SCHEMBL6708265 | 0.84 | ALDH1A1 (0.44) | KMT2AALDH1A1SMN1; SMN2MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583139-B1 | Treatment of inflammatory diseases; inflammatory brain diseases such as multiple sclerosis; N-(Toluene-4-sulfonyl)-L-prolyl-4-(alpha -methylbenzyloxy)-L-phenylalanine; Very Late Antigen 4 | BIOGEN IDEC INTERNATIONAL HOLDING LTD. (BM) | 2003-06-24 | — | — | US | claimed |