Sugi Predict

Sugi Predict / Compounds / SCHEMBL7189356

SCHEMBL7189356

SCHEMBL7189356

COC(C)OOC(=O)C(C(=O)c1c(C)cc(C)cc1C)c1ccccc1.O=[PH3]

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.35
▸ LMNA P02545 3/20 0.34
▸ GAA P10253 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ KMT2A Q03164 2/20 0.33
▸ KEAP1 Q14145 1/20 0.33
▸ NFE2L2 Q16236 1/20 0.33
▸ MMP8 P22894 1/20 0.33
▸ NPSR1 Q6W5P4 2/20 0.33
▸ PPARA Q07869 1/20 0.33
▸ PKM P14618 1/20 0.33
▸ SLC6A2 P23975 1/20 0.32
▸ SLC6A4 P31645 1/20 0.32
▸ SLC6A3 Q01959 1/20 0.32
▸ PTGS1 P23219 1/20 0.32
▸ PTGS2 P35354 1/20 0.32
▸ MEN1 O00255 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7175831 0.90 L3MBTL1 (0.42) L3MBTL1LMNAGAAHTTALDH1A1
SCHEMBL7187443 0.90 KMT2A (0.34) L3MBTL1LMNAGAAHTTALDH1A1
SCHEMBL7189388 0.88 KMT2A (0.35) L3MBTL1LMNAGAAHTTALDH1A1
SCHEMBL7177876 0.83 KMT2A (0.46) L3MBTL1LMNAALDH1A1KMT2AMMP8
SCHEMBL7181511 0.83 ALDH1A1 (0.38) L3MBTL1LMNAGAAALDH1A1KMT2A
SCHEMBL7177979 0.82 CA12 (0.41) L3MBTL1LMNAHTTALDH1A1KMT2A
SCHEMBL7182703 0.82 POLB (0.38) L3MBTL1LMNAALDH1A1KMT2APTGS1
SCHEMBL7180935 0.81 KMT2A (0.37) L3MBTL1LMNAALDH1A1KMT2ANPSR1
SCHEMBL7180176 0.81 L3MBTL1 (0.38) L3MBTL1LMNAGAAHTTALDH1A1
SCHEMBL7183564 0.80 MMP8 (0.54) L3MBTL1GAAKMT2AMMP8SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 L3MBTL1 302/4885LMNA 3241/4885GAA 4753/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 L3MBTL1 126/4885LMNA 3247/4885GAA 4793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.