Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.57 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.51 |
| ▸ | OGA | O60502 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CCR3 | P51677 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15033022 | 0.84 | ALDH1A1 (0.51) | SMN1; SMN2KDM4EHSD17B10MAPK1DRD4 | |
| SCHEMBL28343653 | 0.82 | KDM4E (0.60) | SMN1; SMN2KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL9616882 | 0.81 | KMT2A (0.65) | SMN1; SMN2KDM4EHSD17B10SIGMAR1MEN1 | |
| SCHEMBL10210904 | 0.81 | KDM4E (0.63) | SMN1; SMN2KDM4EHSD17B10MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6580775 | 0.81 | KDM4E (0.59) | HTTSMN1; SMN2KDM4EHSD17B10MEN1 | |
| SCHEMBL6585398 | 0.80 | HDAC3 (0.56) | SMN1; SMN2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL28746194 | 0.79 | ALDH1A1 (0.68) | HTTKDM4EMAPK1MEN1KMT2A | |
| SCHEMBL25145993 | 0.79 | LMNA (0.54) | KDM4ESIGMAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL5216465 | 0.79 | HCRTR1 (0.60) | SMN1; SMN2HSD17B10MAPK1ALDH1A1 | |
| SCHEMBL8681974 | 0.77 | MEN1 (0.62) | KDM4EHSD17B10MAPK1SIGMAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583177-B2 | Amidinophenol derivatives as leukotriene B4 (LTB4)antagonists, phospholipase A2 inhibitors, and trypsin inhibitors. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-06-24 | — | — | US | disclosed |
| US-20020128315-A1 | Leukotriene B4 antagonist compounds and method for treatment | NAKAI HISAO (JP) | 2002-09-12 | — | — | US | disclosed |
| US-6262114-B1 | NOVEL AMIDINOPHENOL DERIVATIVES; INHIBITORS OF PHOSPHOLIPASE A2 AND/OR TRYPSIN | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-07-17 | — | — | US | disclosed |
| EP-0703216-B1 | Amidinophenol derivatives as protease inhibitors | ONO PHARMACEUTICAL CO (JP) | 1999-04-07 | — | — | EP | disclosed |
| EP-0703216-A1 | Amidinophenol derivatives as protease inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-03-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128315-A1 | Leukotriene B4 antagonist compounds and method for treatment | LTB4R2, LTB4R, LTA4H | CCR5 2577/4885SLC18A3 3991/4885OGA 4674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.