Sugi Predict

Sugi Predict / Compounds / Lithium

Lithium

Lithium

SCHEMBL7190038

CC(C)Oc1ccc(PC(=O)c2c(Cl)cccc2Cl)c(OC(C)C)c1.[Li]

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RORC P51449 3/20 0.37
▸ ALDH1A1 P00352 3/20 0.37
▸ ELANE P08246 1/20 0.36
▸ POLB P06746 1/20 0.36
▸ IRAK4 Q9NWZ3 1/20 0.36
▸ KMT2A Q03164 3/20 0.36
▸ RXRA P19793 1/20 0.35
▸ RXRB P28702 1/20 0.35
▸ LMNA P02545 2/20 0.35
▸ GAA P10253 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ CNR1 P21554 1/20 0.35
▸ PARP10 Q53GL7 1/20 0.35
▸ CSNK2A1 P68400 2/20 0.35
▸ MEN1 O00255 2/20 0.34
▸ MAPT P10636 1/20 0.34
▸ ALOX12 P18054 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7190032 0.97 RORC (0.37) RORCALDH1A1ELANEPOLBIRAK4
Lithium SCHEMBL7183504 0.94 BRPF1 (0.39) ALDH1A1ELANEKMT2ALMNAHPGD
Lithium SCHEMBL7189444 0.94 TYK2 (0.36) RORCALDH1A1ELANEPOLBIRAK4
SCHEMBL7183497 0.92 BRPF1 (0.39) ALDH1A1ELANEKMT2ALMNAHPGD
SCHEMBL7189441 0.92 TYK2 (0.36) RORCALDH1A1ELANEPOLBIRAK4
Lithium SCHEMBL7177679 0.87 ALDH1A1 (0.37) ALDH1A1POLBIRAK4KMT2ARXRA
Lithium SCHEMBL7188428 0.86 BRPF1 (0.41) ALDH1A1POLBIRAK4KMT2ALMNA
Lithium SCHEMBL7182005 0.85 DHODH (0.35) HPGDMAPTSMN1; SMN2
SCHEMBL7177481 0.85 SMN1; SMN2 (0.33) ALDH1A1ELANEKMT2ALMNAMEN1
SCHEMBL7187692 0.84 ALDH1A1 (0.38) ALDH1A1POLBKMT2ARXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 RORC 1336/4885ALDH1A1 3416/4885ELANE 4357/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 RORC 1254/4885ALDH1A1 3984/4885ELANE 4460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.