Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 7/20 | 0.36 |
| ▸ | FEN1 | P39748 | 7/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL720147 | 0.87 | MEN1 (0.34) | ALOX5APFEN1SLC6A3KDM4EPKM | |
| SCHEMBL1115136 | 0.86 | KDM4E (0.39) | TAS1R3TAS1R1TAS1R2KDM4EPKM | |
| SCHEMBL30151443 | 0.86 | KDM4E (0.39) | TAS1R3TAS1R1TAS1R2KDM4EPKM | |
| SCHEMBL1223170 | 0.86 | KDM4E (0.39) | TAS1R3TAS1R1TAS1R2KDM4EPKM | |
| SCHEMBL29769728 | 0.85 | KDM4E (0.38) | TAS1R3TAS1R1TAS1R2KDM4EPKM | |
| SCHEMBL679753 | 0.85 | KDM4E (0.38) | TAS1R3TAS1R1TAS1R2KDM4EPKM | |
| SCHEMBL719379 | 0.84 | TAS1R3 (0.38) | TAS1R3TAS1R1TAS1R2KDM4EPKM | |
| SCHEMBL1222941 | 0.84 | MEP1B (0.39) | ALOX5APFEN1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL1918080 | 0.84 | KDM4E (0.37) | TAS1R3TAS1R1TAS1R2KDM4EPKM | |
| SCHEMBL11027447 | 0.83 | KDM4E (0.37) | TAS1R3TAS1R1TAS1R2KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053053-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-03-01 | — | — | US | disclosed |
| US-20120053053-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-03-01 | — | — | US | disclosed |
| US-20120053053-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053053-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | DPYD, DHODH, TYMP | ALOX5AP 1369/4885FEN1 456/4885SLC6A3 2591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.