SCHEMBL7192129

SCHEMBL7192129

COc1c(F)cc(C(=O)c2ccccc2)cc1F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.50
ALDH1A1 P00352 2/20 0.50
HPGD P15428 3/20 0.49
CYP1A2 P05177 2/20 0.49
CYP2D6 P10635 2/20 0.49
CYP2C19 P33261 2/20 0.49
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
ACHE P22303 1/20 0.48
TUBB4A P04350 5/20 0.47
TUBB P07437 5/20 0.47
TUBA3C P0DPH7 5/20 0.47
TUBA1B P68363 5/20 0.47
TUBA4A P68366 5/20 0.47
TUBB4B P68371 5/20 0.47
TUBB3 Q13509 5/20 0.47
TUBB2A Q13885 5/20 0.47
TUBB8 Q3ZCM7 5/20 0.47
TUBA3E Q6PEY2 5/20 0.47
TUBA1A Q71U36 5/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7974528 0.80 LMNA (0.48) ATMALDH1A1HPGDCYP1A2CYP2D6
SCHEMBL2450750 0.80 TUBB4A (0.72) ATMALDH1A1HPGDCYP1A2CYP2D6
SCHEMBL6131922 0.79 ACHE (0.71) ATMALDH1A1HPGDCYP1A2CYP2D6
SCHEMBL1458628 0.79 LMNA (0.58) ALDH1A1HPGDTDP1TUBB1LMNA
SCHEMBL3974706 0.79 ALDH1A1 (0.61) ATMALDH1A1HPGDTDP1L3MBTL1
SCHEMBL7197434 0.77 AKR1B1 (0.61) ATMALDH1A1HPGDTDP1L3MBTL1
SCHEMBL10954888 0.77 MAPT (0.48) ATMALDH1A1HPGDCYP1A2CYP2D6
SCHEMBL11525100 0.76 CYP2C9 (0.51) ATMALDH1A1HPGDCYP1A2CYP2D6
SCHEMBL23231693 0.76 MAPT (0.47) ALDH1A1HPGDCYP1A2CYP2D6CYP2C19
SCHEMBL27569983 0.76 TNFRSF1A (0.61) ATMALDH1A1HPGDCYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6649697-B2 For use in high temperature end-use products such as hot water pipes POLYPLUS CO., LTD. (KR) 2003-11-18 US disclosed
US-20020099139-A1 Dendritic polyetherketone and heat-resistant blend of PVC with the same YOUNG CHANG CHEMICAL CO., LTD. 2002-07-25 US disclosed
US-6388011-B1 CONTAINING 3,5-BIS(2,3,4,5,6-PENTAFLUOROPHENYL)CARBONYL)PHENOXY)-4-HYDROXYBENZOPHENONE YOUNG CHOW CHEMICAL CO., LTD. (KR) 2002-05-14 US disclosed